MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytes. - Wikidata - awgldk - TriplyDB

MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytes.

MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytes.

http://www.wikidata.org/entity/Q36903284

about

Epigenetic regulation in chondrocyte phenotype maintenance for cell-based cartilage repair Roles of microRNA and signaling pathway in osteoarthritis pathogenesis Current Status and Strategy of microRNA Research for Cartilage Development and Osteoarthritis Pathogenesis Review of Prospects of Biological Fluid Biomarkers in Osteoarthritis.Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1β-stimulated production of chemokines and matrix-degrading enzymes in vitro.Significance of epigenetic landscape in cartilage regeneration from the cartilage development and pathology perspective.miR-105/Runx2 axis mediates FGF2-induced ADAMTS expression in osteoarthritis cartilage.MicroRNAs in cartilage development, homeostasis, and disease.Reciprocal inhibition between miR-26a and NF-κB regulates obesity-related chronic inflammation in chondrocytes MicroRNAs' Involvement in Osteoarthritis and the Prospects for Treatments.MicroRNA variants as genetic determinants of bone mass MiR-29a and MiR-140 Protect Chondrocytes against the Anti-Proliferation and Cell Matrix Signaling Changes by IL-1β The Role of miRNAs in Cartilage Homeostasis.Overexpression of microRNA-634 suppresses survival and matrix synthesis of human osteoarthritis chondrocytes by targeting PIK3R1 Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion Cannabinoid WIN‑55,212‑2 mesylate inhibits ADAMTS‑4 activity in human osteoarthritic articular chondrocytes by inhibiting expression of syndecan‑1.Cartilage tissue engineering: recent advances and perspectives from gene regulation/therapy.miR-96 promotes osteogenic differentiation by suppressing HBEGF-EGFR signaling in osteoblastic cells.Intra-articular Delivery of Antago-miR-483-5p Inhibits Osteoarthritis by Modulating Matrilin 3 and Tissue Inhibitor of Metalloproteinase 2.Role of MicroRNA in Osteoarthritis.IL-1β promotes ADAMTS enzyme-mediated aggrecan degradation through NF-κB in human intervertebral disc.Predicted overlapping microRNA regulators of acetylcholine packaging and degradation in neuroinflammation-related disorders.MicroRNA-145 attenuates TNF-α-driven cartilage matrix degradation in osteoarthritis via direct suppression of MKK4.Mesenchymal Stem Cells for Cartilage Regeneration of TMJ Osteoarthritis.Circulating miR-125b but not miR-125a correlates with acute exacerbations of chronic obstructive pulmonary disease and the expressions of inflammatory cytokines.Extracellular genomic biomarkers of osteoarthritis.Onset and Progression of Human Osteoarthritis-Can Growth Factors, Inflammatory Cytokines, or Differential miRNA Expression Concomitantly Induce Proliferation, ECM Degradation, and Inflammation in Articular Cartilage?

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MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytes.

http://www.wikidata.org/entity/Q36903284

description

2013 nî lūn-bûn

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2013年论文

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name

MicroRNA-125b regulates the ex ...... n osteoarthritic chondrocytes.

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MicroRNA-125b regulates the ex ...... n osteoarthritic chondrocytes.

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MicroRNA-125b regulates the ex ...... n osteoarthritic chondrocytes.

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Arthritis Research and Therapy

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MicroRNA-125b regulates the ex ...... n osteoarthritic chondrocytes.

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Hideki Hiraiwa

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Hiroshi Asahara

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Hiroyuki Nakahara

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Martin K Lotz

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Motoshige Nakashima

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Naoki Ishiguro

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Shinya Ishizuka

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Tadahiro Sakai

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Takashi Hamada

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Tetsuya Matsukawa

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P2860

Principles of microRNA-target recognition

An extensive class of small RNAs in Caenorhabditis elegans

An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

Identification of novel genes coding for small expressed RNAs

MicroRNAs: genomics, biogenesis, mechanism, and function

The ADAMTS metalloproteinases

MicroRNA biogenesis: coordinated cropping and dicing

MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses

Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.

MicroRNA-140 plays dual roles in both cartilage development and homeostasis.

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