Promoter hypermethylation of the tumor-suppressor genes ITIH5, DKK3, and RASSF1A as novel biomarkers for blood-based breast cancer screening. - Wikidata - awgldk - TriplyDB

Promoter hypermethylation of the tumor-suppressor genes ITIH5, DKK3, and RASSF1A as novel biomarkers for blood-based breast cancer screening.

Promoter hypermethylation of the tumor-suppressor genes ITIH5, DKK3, and RASSF1A as novel biomarkers for blood-based breast cancer screening.

http://www.wikidata.org/entity/Q36903459

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Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential Blood-based DNA methylation as biomarker for breast cancer: a systematic review Breast cancer epidemic in the early twenty-first century: evaluation of risk factors, cumulative questionnaires and recommendations for preventive measures.Patients and Methods of the PATH Biobank - A Resource for Breast Cancer Research Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/β-catenin signalling and apoptosis regulation in breast cancer cells SOCS3 promoter hypermethylation is a favorable prognosticator and a novel indicator for G-CIMP-positive GBM patients.Screening tests: a review with examples AGR3 in breast cancer: prognostic impact and suitable serum-based biomarker for early cancer detection.Aberrant methylation patterns in cancer: a clinical view.Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts.Genome-wide in vivo RNAi screen identifies ITIH5 as a metastasis suppressor in pancreatic cancer.Interleukin-6 Induced "Acute" Phenotypic Microenvironment Promotes Th1 Anti-Tumor Immunity in Cryo-Thermal Therapy Revealed By Shotgun and Parallel Reaction Monitoring Proteomics.Methylated DNA and microRNA in body fluids as biomarkers for cancer detection.DNA methylation profile of triple negative breast cancer-specific genes comparing lymph node positive patients to lymph node negative patients Circulating cell-free DNA-based epigenetic assay can detect early breast cancer.Circulating nucleic acids as biomarkers in breast cancer.CancerLocator: non-invasive cancer diagnosis and tissue-of-origin prediction using methylation profiles of cell-free DNA.Diagnostic and prognostic value of circulating tumor-related DNA in cancer patients.Dysregulated expression of dickkopfs for potential detection of hepatocellular carcinoma.Effects of deranged metabolism on epigenetic changes in cancer.Diagnostic and prognostic epigenetic biomarkers in cancer.A 2015 survey of established or potential epigenetic biomarkers for the accurate detection of human cancers.Towards DNA methylation detection using biosensors.The heparan sulfate sulfotransferase 3-OST3A (HS3ST3A) is a novel tumor regulator and a prognostic marker in breast cancer.Helicobacter pylori-induced modulation of the promoter methylation of Wnt antagonist genes in gastric carcinogenesis.Epigenetic inactivation of the novel candidate tumor suppressor gene ITIH5 in colon cancer predicts unfavorable overall survival in the CpG island methylator phenotype.Methylation profiling of 48 candidate genes in tumor and matched normal tissues from breast cancer patients.The evidence base for circulating tumour DNA blood-based biomarkers for the early detection of cancer: a systematic mapping review.Liquid biopsy in colon cancer: comparison of different circulating DNA extraction systems following absolute quantification of KRAS mutations using Intplex allele-specific PCR.Methods for genome-wide DNA methylation analysis in human cancer.Multigene methylation analysis of enriched circulating tumor cells associates with poor progression-free survival in metastatic breast cancer patients.Using Resistin, glucose, age and BMI to predict the presence of breast cancer.Dickkopf Homolog 3 (DKK3): a candidate for detection and treatment of cancers?Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett's esophagus.High-frequency deregulated expression of Wnt signaling pathway members in breast carcinomas.The role of epigenomics in personalized medicine.Gene promoter hypermethylation is found in sentinel lymph nodes of breast cancer patients, in samples identified as positive by one-step nucleic acid amplification of cytokeratin 19 mRNA.[Liquid biopsy analysis using cell-free DNA (cfDNA): Opportunities and limitations].Methylation analysis of plasma cell-free DNA for breast cancer early detection using bisulfite next-generation sequencing.Methylation status and protein expression of RASSF1A in breast cancer patients.

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Promoter hypermethylation of the tumor-suppressor genes ITIH5, DKK3, and RASSF1A as novel biomarkers for blood-based breast cancer screening.

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Birte Becker

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Edgar Dahl

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Kirsten Winner

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Michael G Schrauder

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P2860

Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours

Global cancer statistics

MethyLight: a high-throughput assay to measure DNA methylation

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

The power and the promise of DNA methylation markers

Screening mammography in women 40 to 49 years of age: a systematic review for the American College of Physicians

Quantitative assessment of promoter hypermethylation during breast cancer development

Hypermethylation of tumor suppressor genes involved in critical regulatory pathways for developing a blood-based test in breast cancer.

Promoter methylation and the detection of breast cancer

Breast density as a predictor of mammographic detection: comparison of interval- and screen-detected cancers.

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1

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