Large-scale sequence and structural comparisons of human naive and antigen-experienced antibody repertoires.
about
ABodyBuilder: Automated antibody structure prediction with data-driven accuracy estimation.Antibodyomics: bioinformatics technologies for understanding B-cell immunity to HIV-1.Exploring Human Antimicrobial Antibody Responses on a Single B Cell Level.Transitional B Cells in Early Human B Cell Development - Time to Revisit the Paradigm?Efficient affinity maturation of antibody variable domains requires co-selection of compensatory mutations to maintain thermodynamic stability.Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires.Temporal stability and molecular persistence of the bone marrow plasma cell antibody repertoire.Analysis of 5518 unique, productively rearranged human VH3-23*01 gene sequences reveals CDR-H3 length-dependent usage of the IGHD2 gene family.Immune history and influenza virus susceptibility.Significant Differences in Physicochemical Properties of Human Immunoglobulin Kappa and Lambda CDR3 Regions.Structure-based cross-docking analysis of antibody-antigen interactions.How B-Cell Receptor Repertoire Sequencing Can Be Enriched with Structural Antibody Data.On being the right size: antibody repertoire formation in the mouse and human.Functional interrogation and mining of natively paired human VH:VL antibody repertoires.Integrating high-throughput screening and sequencing for monoclonal antibody discovery and engineering.Arginine mutations in antibody complementarity-determining regions display context-dependent affinity/specificity trade-offs.Accurate Structure Prediction of CDR H3 Loops Enabled by a Novel Structure-Based C-Terminal Constraint.High-Throughput Single-Cell Analysis of B Cell Receptor Usage among Autoantigen-Specific Plasma Cells in Celiac Disease.Insights into the Structural Basis of Antibody Affinity Maturation from Next-Generation Sequencing.In-Depth Analysis of Human Neonatal and Adult IgM Antibody Repertoires.A natively paired antibody library yields drug leads with higher sensitivity and specificity than a randomly paired antibody library.Coupling of Single Molecule, Long Read Sequencing with IMGT/HighV-QUEST Analysis Expedites Identification of SIV gp140-Specific Antibodies from scFv Phage Display Libraries.Analyzing Immunoglobulin Repertoires.Simple paired heavy- and light-chain antibody repertoire sequencing using endoplasmic reticulum microsomes.Many Routes to an Antibody Heavy-Chain CDR3: Necessary, Yet Insufficient, for Specific Binding.Repertoire Analysis of Antibody CDR-H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification.TCRmodel: high resolution modeling of T cell receptors from sequence.Immunoglobulin gene analysis as a tool for investigating human immune responses.
P2860
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P2860
Large-scale sequence and structural comparisons of human naive and antigen-experienced antibody repertoires.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Large-scale sequence and struc ...... erienced antibody repertoires.
@en
type
label
Large-scale sequence and struc ...... erienced antibody repertoires.
@en
prefLabel
Large-scale sequence and struc ...... erienced antibody repertoires.
@en
P2093
P2860
P50
P356
P1476
Large-scale sequence and struc ...... erienced antibody repertoires.
@en
P2093
Andrew D Ellington
Brandon J DeKosky
Constantine Chrysostomou
Erik L Johnson
George Georgiou
Jeffrey J Gray
Oana I Lungu
Wissam Charab
P2860
P304
P356
10.1073/PNAS.1525510113
P407
P577
2016-04-25T00:00:00Z