Organization and expression of the immediate early genes of human cytomegalovirus
about
Autorepression of the human cytomegalovirus major immediate-early promoter/enhancer at late times of infection is mediated by the recruitment of chromatin remodeling enzymes by IE86Prolonged activation of NF-kappaB by human cytomegalovirus promotes efficient viral replication and late gene expressionSimilarity in viral and host promoters couples viral reactivation with host cell migrationDisruption of PML subnuclear domains by the acidic IE1 protein of human cytomegalovirus is mediated through interaction with PML and may modulate a RING finger-dependent cryptic transactivator function of PMLTranscription factor Sp1 mediates cell-specific trans-activation of the human cytomegalovirus DNA polymerase gene promoter by immediate-early protein IE86 in glioblastoma U373MG cells.Phosphorylation of the human cytomegalovirus 86-kilodalton immediate-early protein IE2.A cis repression sequence adjacent to the transcription start site of the human cytomegalovirus US3 gene is required to down regulate gene expression at early and late times after infectionThe human cytomegalovirus major immediate-early distal enhancer region is required for efficient viral replication and immediate-early gene expression.Covalent modification of the transactivator protein IE2-p86 of human cytomegalovirus by conjugation to the ubiquitin-homologous proteins SUMO-1 and hSMT3b.DNA microarrays of the complex human cytomegalovirus genome: profiling kinetic class with drug sensitivity of viral gene expression.Exon 3 of the human cytomegalovirus major immediate-early region is required for efficient viral gene expression and for cellular cyclin modulation.Evaluation of interactions of human cytomegalovirus immediate-early IE2 regulatory protein with small ubiquitin-like modifiers and their conjugation enzyme Ubc9Multiple transforming regions of human cytomegalovirus DNA.An AP-1 binding site is the predominant cis-acting regulatory element in the 1.2-kilobase early RNA promoter of human cytomegalovirus.Inhibition of cyclooxygenase 2 blocks human cytomegalovirus replication.Lipopolysaccharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes.Binding of transcription factors and creation of a large nucleoprotein complex on the human cytomegalovirus enhancer.Glucocorticosteroids trigger reactivation of human cytomegalovirus from latently infected myeloid cells and increase the risk for HCMV infection in D+R+ liver transplant patients.Presentation of an immunodominant immediate-early CD8+ T cell epitope resists human cytomegalovirus immunoevasion.High prevalence of latently present cytomegalovirus in arterial walls of patients suffering from grade III atherosclerosis.The presence of cytomegalovirus nucleic acids in arterial walls of atherosclerotic and nonatherosclerotic patientsAnalysis and mapping of a family of 3'-coterminal transcripts containing coding sequences for human cytomegalovirus open reading frames UL93 through UL99.Isolation and characterization of a low-abundance splice variant from the human cytomegalovirus major immediate-early gene region.Multiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infectionReversal of human cytomegalovirus major immediate-early enhancer/promoter silencing in quiescently infected cells via the cyclic AMP signaling pathway.The human cytomegalovirus virion possesses an activated casein kinase II that allows for the rapid phosphorylation of the inhibitor of NF-kappaB, IkappaBalpha.The IE2 regulatory protein of human cytomegalovirus induces expression of the human transforming growth factor beta1 gene through an Egr-1 binding site.The major immediate-early proteins IE1 and IE2 of human cytomegalovirus colocalize with and disrupt PML-associated nuclear bodies at very early times in infected permissive cells.Artemisinin-derived dimer diphenyl phosphate is an irreversible inhibitor of human cytomegalovirus replication.HCMV Displays a Unique Transcriptome of Immunomodulatory Genes in Primary Monocyte-Derived Cell Types.Promoter-regulatory region of the major immediate early gene of human cytomegalovirusHuman cytomegalovirus immediate early interaction with host nuclear structures: definition of an immediate transcript environment.Precise localization of genes on large animal virus genomes: use of lambda gt11 and monoclonal antibodies to map the gene for a cytomegalovirus protein family.Cloning and physical mapping of a gene fragment coding for a 64-kilodalton major late antigen of human cytomegalovirus.Inhibition of IL-1beta transcription by peptides derived from the hCMV IE2 transactivator.Identification of sequence elements in the human cytomegalovirus DNA polymerase gene promoter required for activation by viral gene products.Nucleotide sequence analysis of a 38.5-kilobase-pair region of the genome of human herpesvirus 6 encoding human cytomegalovirus immediate-early gene homologs and transactivating functionsThe human cytomegalovirus 86-kilodalton immediate-early 2 protein: synthesis as a precursor polypeptide and interaction with a 75-kilodalton protein of probable viral origin.Acquisition of cytomegalovirus infection: an update.Use of recombinant virus to assess human cytomegalovirus early and late promoters in the context of the viral genome.
P2860
Q24670535-66E63BAB-D5FA-4D66-9F1B-0F87C11BF28DQ28193489-CEE76C5B-66FF-44D6-85DA-BC3ADCE88E04Q33640033-D1BC50AB-FD2B-4980-85BB-C6DBCE2349B2Q33776312-03F6F8B4-AB50-4729-8D85-F85560FF07F8Q33781947-260480CC-169F-4879-A61D-EFE28561F270Q33784945-4FC5AEE4-28ED-46D7-AB08-9368B613CF58Q33785972-CCD0A1FA-DC08-4FF7-8188-1087D8A5C53FQ33797024-9ECAEE92-7AEC-4D44-9B45-B0DCDFED991AQ33799527-8285718C-60C3-48B0-A086-5276CB2ACD14Q33815575-17A698D4-269F-45A0-B4FF-9BA7DF1D4461Q33843191-20BB1F92-01BE-411E-8220-DCB639CE5629Q33851361-59CC5172-E543-42DE-9151-8C5C557C1DBEQ33928670-D1FE68E5-9BA5-44AF-914A-59B602EFD340Q33932764-02D49E78-87E5-4F07-9BC5-6CD09E3A7369Q34021267-F753BDE3-0774-4F6B-BF1E-C0B1D1AAC6DEQ34121357-0EF87C31-A8F2-440E-AF06-7BA59C954602Q34626976-B32170B7-829F-4D03-B77A-587DEA6A7F34Q34720787-6C1E54DD-8EDC-47F3-AC64-ED829764CBBCQ34743762-23854A12-0672-477C-9942-19511E429A77Q35811381-BF32AD14-BBCE-4CE6-9246-2BDC1344AB9EQ35816869-DDBABEF8-8A44-47E4-9E30-BC76A4171B1CQ35834103-41E4688B-9663-43C8-9793-73AA50592F42Q35840154-A9C5E145-24F7-4109-89CC-C4C6CB7BB458Q35853699-E4128269-70E5-471C-9A97-A9D99FEC55B8Q35857316-3881D827-A382-45D4-AED6-F33A0ACD32E6Q35857513-D1902F86-EF1B-48CB-AAEA-8DDFC4D0F220Q35870737-870BB810-0BBF-4B62-98F1-420213DE1410Q35886859-674C8D14-BD12-4EA3-873B-AA31D4AD2D83Q36086432-3409E7CC-4192-4B10-B1DF-8E42D3E9B94BQ36168094-9F98111F-7103-4C83-B9E8-3A93760B2FF4Q36252923-1AFF05D9-D2C6-4AA0-84DD-ED90EA1553CAQ36274309-DA60AEAB-FC5E-4158-A215-8F14C952DF5AQ36422995-21D66063-F41D-4227-B3F3-CB5843D38CFEQ36586660-2FD551B6-28B5-4758-A733-B8E379A91578Q36620691-AAF9886F-7CA5-4FD0-8A61-3E5D56EA7103Q36621424-F18E918E-4240-46B4-B19E-DBFF1E7B196EQ36626298-62E9B3A0-BE84-42A9-802E-7A6C2E8AC046Q36626536-7452C102-F939-4500-A2CC-8F748F03B1DCQ36635110-B45A6C83-CC1B-4FAE-A3FA-65919F57337DQ36636303-8C11E801-7B59-45F5-88C7-087120AEB515
P2860
Organization and expression of the immediate early genes of human cytomegalovirus
description
1983 nî lūn-bûn
@nan
1983年の論文
@ja
1983年論文
@yue
1983年論文
@zh-hant
1983年論文
@zh-hk
1983年論文
@zh-mo
1983年論文
@zh-tw
1983年论文
@wuu
1983年论文
@zh
1983年论文
@zh-cn
name
Organization and expression of the immediate early genes of human cytomegalovirus
@en
type
label
Organization and expression of the immediate early genes of human cytomegalovirus
@en
prefLabel
Organization and expression of the immediate early genes of human cytomegalovirus
@en
P2093
P2860
P1433
P1476
Organization and expression of the immediate early genes of human cytomegalovirus
@en
P2093
D R Thomsen
L C Goldstein
M F Stinski
R M Stenberg
P2860
P407
P577
1983-04-01T00:00:00Z