Epidermal growth factor receptor and K-Ras mutations and resistance of lung cancer to insulin-like growth factor 1 receptor tyrosine kinase inhibitors
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Implications of Insulin-like Growth Factor 1 Receptor Activation in Lung CancerThe links between insulin resistance, diabetes, and cancerCompounds from the marine sponge Cribrochalina vasculum offer a way to target IGF-1R mediated signaling in tumor cellsSynergistic apoptosis in head and neck squamous cell carcinoma cells by co-inhibition of insulin-like growth factor-1 receptor signaling and compensatory signaling pathways.Phase I Dose-Escalation Study of Linsitinib (OSI-906) and Erlotinib in Patients with Advanced Solid Tumors.Metabotropic glutamate receptor 1 mediates melanocyte transformation via transactivation of insulin-like growth factor 1 receptor.Can we unlock the potential of IGF-1R inhibition in cancer therapy?Redundant kinase activation and resistance of EGFR-tyrosine kinase inhibitors.Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis.Targeting the insulin-like growth factor receptor and Src signaling network for the treatment of non-small cell lung cancer.Mutational analysis of the insulin-like growth factor 1 receptor tyrosine kinase domain in non-small cell lung cancer patients.Prognostic implications of tumoral expression of insulin like growth factors 1 and 2 in patients with non-small-cell lung cancer.Co-Targeting IGF-1R and Autophagy Enhances the Effects of Cell Growth Suppression and Apoptosis Induced by the IGF-1R Inhibitor NVP-AEW541 in Triple-Negative Breast Cancer Cells.Novel C6-substituted 1,3,4-oxadiazinones as potential anti-cancer agents.Class act: safety comparison of approved tyrosine kinase inhibitors for non-small-cell lung carcinoma.Phosphorylated insulin-like growth factor-1 receptor (pIGF1R) is a poor prognostic factor in brain metastases from lung adenocarcinomas.Phosphoprotein analysis reveals MEK inhibition as a way to target non-small cell lung cancer tumor initiating cells.Metabolic recovery of lipodystrophy, liver steatosis, and pancreatic β cell proliferation after the withdrawal of OSI-906.Oncogenic KRAS confers chemoresistance by upregulating NRF2.Molecular genetics and cellular events of K-Ras-driven tumorigenesis.Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity.
P2860
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P2860
Epidermal growth factor receptor and K-Ras mutations and resistance of lung cancer to insulin-like growth factor 1 receptor tyrosine kinase inhibitors
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Epidermal growth factor recept ...... tor tyrosine kinase inhibitors
@en
type
label
Epidermal growth factor recept ...... tor tyrosine kinase inhibitors
@en
prefLabel
Epidermal growth factor recept ...... tor tyrosine kinase inhibitors
@en
P2093
P2860
P356
P1433
P1476
Epidermal growth factor recept ...... tor tyrosine kinase inhibitors
@en
P2093
Bonnie Glisson
Bryan Hennessy
Edward S Kim
Ho-Young Lee
J Jack Lee
Ju-Seog Lee
Ludmila Prudkin
Scott M Lippman
Waun Ki Hong
P2860
P304
P356
10.1002/CNCR.26656
P407
P577
2012-02-22T00:00:00Z