Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia
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Chimeric Antigen Receptor-Modified T Cells for Solid Tumors: Challenges and ProspectsCAR T cells for solid tumors: armed and ready to go?Fibroblast activation protein α in tumor microenvironment: recent progression and implications (review)Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity.Concise Review: Paracrine Functions of Vascular Niche Cells in Regulating Hematopoietic Stem Cell FateFrom isolation to implantation: a concise review of mesenchymal stem cell therapy in bone fracture repair.Stromal reengineering to treat pancreas cancerPharmacokinetics and toxicology of a fibroblast activation protein (FAP)-activated prodrug in murine xenograft models of human cancer.Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8+ T cells.Fibroblast activation protein expression by stromal cells and tumor-associated macrophages in human breast cancer.Safety of targeting ROR1 in primates with chimeric antigen receptor-modified T cells.Fibroblast activation protein (FAP) is essential for the migration of bone marrow mesenchymal stem cells through RhoA activationFibroblast activation protein-α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterationsTumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells.The bone marrow niche for haematopoietic stem cells.Genetically modified T-cell therapy for osteosarcomaFibroblast activation protein is dispensable in the anti-influenza immune response in mice.A potent immunotoxin targeting fibroblast activation protein for treatment of breast cancer in miceSuicide Gene-Engineered Stromal Cells Reveal a Dynamic Regulation of Cancer Metastasis.Cancer prevention and therapy through the modulation of the tumor microenvironment.Depletion of FAP+ cells reduces immunosuppressive cells and improves metabolism and functions CD8+T cells within tumorsCathepsin C is a tissue-specific regulator of squamous carcinogenesis.Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs.Roles of nonmyogenic mesenchymal progenitors in pathogenesis and regeneration of skeletal muscle.EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss.Design and implementation of adoptive therapy with chimeric antigen receptor-modified T cells.Adoptive immunotherapy for cancer or viruses.Moving receptor redirected adoptive cell therapy toward fine tuning of antitumor responses.Generation of Potent T-cell Immunotherapy for Cancer Using DAP12-Based, Multichain, Chimeric ImmunoreceptorsCAR T-cell therapy: toxicity and the relevance of preclinical models.Cancer-associated fibroblasts as target and tool in cancer therapeutics and diagnostics.Prospects for adoptive immunotherapy of pancreatic cancer using chimeric antigen receptor-engineered T-cells.CAR T-cell immunotherapy: The path from the by-road to the freeway?A COL11A1-correlated pan-cancer gene signature of activated fibroblasts for the prioritization of therapeutic targets.Tumor Regression and Delayed Onset Toxicity Following B7-H4 CAR T Cell Therapy.Driving gene-engineered T cell immunotherapy of cancer.Can Targeting Stroma Pave the Way to Enhanced Antitumor Immunity and Immunotherapy of Solid Tumors?The expression of proline-specific enzymes in the human lungExpression of anti-VEGF antibody together with anti-EGFR or anti-FAP enhances tumor regression as a result of vaccinia virotherapy.Chimeric antigen receptor-engineered T cells for liver cancers, progress and obstacles.
P2860
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P2860
Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Immune targeting of fibroblast ...... row stromal cells and cachexia
@en
type
label
Immune targeting of fibroblast ...... row stromal cells and cachexia
@en
prefLabel
Immune targeting of fibroblast ...... row stromal cells and cachexia
@en
P2093
P2860
P356
P1476
Immune targeting of fibroblast ...... row stromal cells and cachexia
@en
P2093
Dhanalakshmi Chinnasamy
Richard A Morgan
Steven A Rosenberg
P2860
P304
P356
10.1084/JEM.20130110
P407
P577
2013-05-27T00:00:00Z