PKA phosphorylation of cardiac ryanodine receptor modulates SR luminal Ca2+ sensitivity.
about
Genetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling.Obesity Resistance Promotes Mild Contractile Dysfunction Associated with Intracellular Ca2+ HandlingCa²⁺-dependent phosphorylation of Ca²⁺ cycling proteins generates robust rhythmic local Ca²⁺ releases in cardiac pacemaker cells.Role of RyR2 phosphorylation in heart failure and arrhythmias: Controversies around ryanodine receptor phosphorylation in cardiac disease.ß-Adrenergic stimulation increases RyR2 activity via intracellular Ca2+ and Mg2+ regulationMultiple actions of phi-LITX-Lw1a on ryanodine receptors reveal a functional link between scorpion DDH and ICK toxins.Bacopa monnieri extract increases rat coronary flow and protects against myocardial ischemia/reperfusion injury.The Modulation of Cardiac Contractile Function by the Pharmacological and Toxicological Effects of Urocortin2.Sarcoplasmic reticulum Ca2+ cycling protein phosphorylation in a physiologic Ca2+ milieu unleashes a high-power, rhythmic Ca2+ clock in ventricular myocytes: relevance to arrhythmias and bio-pacemaker design.Posttranslational modifications of cardiac ryanodine receptors: Ca(2+) signaling and EC-coupling.Unraveling the exercise-related proteome signature in heart.The ryanodine receptor provides high throughput Ca2+-release but is precisely regulated by networks of associated proteins: a focus on proteins relevant to phosphorylation.Dysregulated Zn2+ homeostasis impairs cardiac type-2 ryanodine receptor and mitsugumin 23 functions, leading to sarcoplasmic reticulum Ca2+ leakage.Regulation of sarcoplasmic reticulum Ca2+ release by serine-threonine phosphatases in the heart.Ablation of the cardiac ryanodine receptor phospho-site Ser2808 does not alter the adrenergic response or the progression to heart failure in mice. Elimination of the genetic background as critical variable.Maximal acceleration of Ca2+ release refractoriness by β-adrenergic stimulation requires dual activation of kinases PKA and CaMKII in mouse ventricular myocytes.Muscarinic Stimulation Facilitates Sarcoplasmic Reticulum Ca Release by Modulating Ryanodine Receptor 2 Phosphorylation Through Protein Kinase G and Ca/Calmodulin-Dependent Protein Kinase II.Hypotonic swelling promotes nitric oxide release in cardiac ventricular myocytes: impact on swelling-induced negative inotropic effect.Age- and strain-related aberrant Ca2+ release is associated with sudden cardiac death in the ACTC E99K mouse model of hypertrophic cardiomyopathy.Functional Characterization and Comparison of Intercellular Communication in Stem Cell-Derived Cardiomyocytes.Genetic ablation of ryanodine receptor 2 phosphorylation at Ser-2808 aggravates Ca(2+)-dependent cardiomyopathy by exacerbating diastolic Ca2+ release.G-protein-coupled receptor 30/adenylyl cyclase/protein kinase A pathway is involved in estradiol 17ß-D-glucuronide-induced cholestasis.
P2860
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P2860
PKA phosphorylation of cardiac ryanodine receptor modulates SR luminal Ca2+ sensitivity.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
PKA phosphorylation of cardiac ryanodine receptor modulates SR luminal Ca2+ sensitivity.
@en
type
label
PKA phosphorylation of cardiac ryanodine receptor modulates SR luminal Ca2+ sensitivity.
@en
prefLabel
PKA phosphorylation of cardiac ryanodine receptor modulates SR luminal Ca2+ sensitivity.
@en
P2093
P2860
P1476
PKA phosphorylation of cardiac ryanodine receptor modulates SR luminal Ca2+ sensitivity.
@en
P2093
Ernst Niggli
Héctor H Valdivia
Nina D Ullrich
P2860
P356
10.1016/J.YJMCC.2012.03.015
P577
2012-04-01T00:00:00Z