Characterizing complex dynamics in the transactivation response element apical loop and motional correlations with the bulge by NMR, molecular dynamics, and mutagenesis
about
Solution structure and dynamics of the wild-type pseudoknot of human telomerase RNAAccommodating variety in iron-responsive elements: Crystal structure of transferrin receptor 1 B IRE bound to iron regulatory protein 1Rapid Exchange Between Free and Bound States in RNA-Dendrimer Polyplexes: Implications on the Mechanism of Delivery and ReleaseCharacterizing RNA ensembles from NMR data with kinematic models.Structural dynamics of a single-stranded RNA-helix junction using NMR.Invisible RNA state dynamically couples distant motifs.Intrinsic nucleic acid dynamics modulates HIV-1 nucleocapsid protein binding to its targets.Dynamic motions of the HIV-1 frameshift site RNA.Unraveling the structural complexity in a single-stranded RNA tail: implications for efficient ligand binding in the prequeuosine riboswitch.Slowdown of Interhelical Motions Induces a Glass Transition in RNACharacterizing RNA dynamics at atomic resolution using solution-state NMR spectroscopyVisualizing transient low-populated structures of RNA.Multivalent Amino Sugars to Recognize Different TAR RNA Conformations.A general method for constructing atomic-resolution RNA ensembles using NMR residual dipolar couplings: the basis for interhelical motions revealed.Utility of 1H NMR chemical shifts in determining RNA structure and dynamicsStructure of a low-population binding intermediate in protein-RNA recognition.How binding of small molecule and peptide ligands to HIV-1 TAR alters the RNA motional landscape.Constructing RNA dynamical ensembles by combining MD and motionally decoupled NMR RDCs: new insights into RNA dynamics and adaptive ligand recognition.Influence of dimethylsulfoxide on RNA structure and ligand binding.Domain-elongation NMR spectroscopy yields new insights into RNA dynamics and adaptive recognition.Shortening the HIV-1 TAR RNA Bulge by a Single Nucleotide Preserves Motional Modes over a Broad Range of Time Scales.Examining the relationship between RNA function and motion using nuclear magnetic resonance.Comparison of solution and crystal structures of preQ1 riboswitch reveals calcium-induced changes in conformation and dynamics.Insights into the mechanisms of RNA secondary structure destabilization by the HIV-1 nucleocapsid protein.Theory of nonrigid rotational motion applied to NMR relaxation in RNA.Slow exchange model of nonrigid rotational motion in RNA for combined solid-state and solution NMR studiesMolecular dynamics simulations identify time scale of conformational changes responsible for conformational selection in molecular recognition of HIV-1 transactivation responsive RNA.Structural and thermodynamic signatures that define pseudotriloop RNA hairpins.Probing sequence-specific DNA flexibility in a-tracts and pyrimidine-purine steps by nuclear magnetic resonance (13)C relaxation and molecular dynamics simulations.Variable helix elongation as a tool to modulate RNA alignment and motional couplings.Ultrahigh resolution characterization of domain motions and correlations by multialignment and multireference residual dipolar coupling NMR.Flipping of the ribosomal A-site adenines provides a basis for tRNA selection.Referencing strategy for the direct comparison of nuclear magnetic resonance and molecular dynamics motional parameters in RNA.RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview.Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR.Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcriptionHIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry
P2860
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P2860
Characterizing complex dynamics in the transactivation response element apical loop and motional correlations with the bulge by NMR, molecular dynamics, and mutagenesis
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Characterizing complex dynamic ...... ular dynamics, and mutagenesis
@en
type
label
Characterizing complex dynamic ...... ular dynamics, and mutagenesis
@en
prefLabel
Characterizing complex dynamic ...... ular dynamics, and mutagenesis
@en
P2093
P2860
P50
P1433
P1476
Characterizing complex dynamic ...... ular dynamics, and mutagenesis
@en
P2093
Elizabeth A Dethoff
Hashim M Al-Hashimi
Ioan Andricioaei
P2860
P304
P356
10.1529/BIOPHYSJ.108.140285
P407
P577
2008-07-11T00:00:00Z