A perfluoroaryl-cysteine S(N)Ar chemistry approach to unprotected peptide stapling.
about
Click chemistry in complex mixtures: bioorthogonal bioconjugationDouble Strain-Promoted Macrocyclization for the Rapid Selection of Cell-Active Stapled PeptidesMotif mediated protein-protein interactions as drug targetsNovel Method for Radiolabeling and Dimerizing Thiolated Peptides Using (18)F-HexafluorobenzeneΠ-Clamp-mediated cysteine conjugationConstraining cyclic peptides to mimic protein structure motifs.Comparative α-helicity of cyclic pentapeptides in water.Atomically precise organomimetic cluster nanomolecules assembled via perfluoroaryl-thiol SNAr chemistryConvergent diversity-oriented side-chain macrocyclization scan for unprotected polypeptides.Enzyme-catalyzed macrocyclization of long unprotected peptides.Designer macrocyclic organo-peptide hybrids inhibit the interaction between p53 and HDM2/X by accommodating a functional α-helix.Bridged Analogues for p53-Dependent Cancer Therapy Obtained by S-AlkylationConformational Restriction of Peptides Using Dithiol Bis-AlkylationOrganic chemistry. Strain-release amination.Organometallic palladium reagents for cysteine bioconjugationAcetone-Linked Peptides: A Convergent Approach for Peptide Macrocyclization and Labeling.Field Guide to Challenges and Opportunities in Antibody-Drug Conjugates for Chemists.The "π-Clamp" Offers a New Strategy for Site-Selective Protein Modification.Enzymatic "click" ligation: selective cysteine modification in polypeptides enabled by promiscuous glutathione S-transferase.Converting disulfide bridges in native peptides to stable methylene thioacetals.In Situ Formation of an Azo Bridge on Proteins Controllable by Visible Light.Modulating protein-protein interactions: the potential of peptides.Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation.Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes.Chemical Protein Modification through Cysteine.Approaches to the stabilization of bioactive epitopes by grafting and peptide cyclization.Designing helical peptide inhibitors of protein-protein interactionsReview stapling peptides using cysteine crosslinking.Bioconjugation - using selective chemistry to enhance the properties of proteins and peptides as therapeutics and carriers.Linear aliphatic dialkynes as alternative linkers for double-click stapling of p53-derived peptides.Macrocycles: lessons from the distant past, recent developments, and future directions.Chiral Sulfoxide-Induced Single Turn Peptide α-Helicity.Thioether-Derived Macrocycle for Peptide Secondary Structure Fixation.Peptide/protein stapling and unstapling: introduction of s-tetrazine, photochemical release, and regeneration of the peptide/protein.Stapled Vasoactive Intestinal Peptide (VIP) Derivatives Improve VPAC2 Agonism and Glucose-Dependent Insulin Secretion.Receptor-templated stapling of intrinsically disordered peptide ligands.Development of a Multifunctional Benzophenone Linker for Peptide Stapling and Photoaffinity Labelling.Synthesis of bioactive and stabilized cyclic peptides by macrocyclization using C(sp3)-H activation.New peptide architectures through C-H activation stapling between tryptophan-phenylalanine/tyrosine residuesPeptide Macrocyclization Inspired by Non-Ribosomal Imine Natural Products.
P2860
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P2860
A perfluoroaryl-cysteine S(N)Ar chemistry approach to unprotected peptide stapling.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
A perfluoroaryl-cysteine S(N)Ar chemistry approach to unprotected peptide stapling.
@en
type
label
A perfluoroaryl-cysteine S(N)Ar chemistry approach to unprotected peptide stapling.
@en
prefLabel
A perfluoroaryl-cysteine S(N)Ar chemistry approach to unprotected peptide stapling.
@en
P2093
P2860
P356
P1476
A perfluoroaryl-cysteine S(N)Ar chemistry approach to unprotected peptide stapling.
@en
P2093
Alexander M Spokoyny
Hongtao Yu
Jingjing J Ling
Yu-Shan Lin
P2860
P304
P356
10.1021/JA400119T
P407
P577
2013-04-16T00:00:00Z