Myeloma mutant with a novel 3' flanking region: loss of normal sequence and insertion of repetitive elements leads to decreased transcription but normal processing of the alpha heavy-chain gene products.
about
The origin of a developmentally regulated Igh replicon is located near the border of regulatory domains for Igh replication and expressionEnhancer complexes located downstream of both human immunoglobulin Calpha genesChromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites.Construction and expression of a recombinant antibody-targeted plasminogen activatorIdentification of 3' alpha-hs4, a novel Ig heavy chain enhancer element regulated at multiple stages of B cell differentiation.Accessibility control and machinery of immunoglobulin class switch recombination.Enhancement of antibody class-switch recombination by the cumulative activity of four separate elements.An enhancer at the 3' end of the mouse immunoglobulin heavy chain locusStrong transcriptional activation of translocated c-myc genes occurs without a strong nearby enhancer or promoterThe 3' end of the heavy chain constant region locus enhances germline transcription and switch recombination of the four gamma genes.Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers.Regulation of the replication of the murine immunoglobulin heavy chain gene locus: evaluation of the role of the 3' regulatory region.The immunoglobulin heavy chain locus contains another B-cell-specific 3' enhancer close to the alpha constant region.Interruption of two immunoglobulin heavy-chain switch regions in murine plasmacytoma P3.26Bu4 by insertion of retroviruslike element ETn.Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3' regulatory region of the immunoglobulin heavy chain locus.Allelic variation and differential expression at the 27-kilodalton zein locus in maize.Role of the Igh intronic enhancer Eμ in clonal selection at the pre-B to immature B cell transition.Transcription of a productively rearranged Ig VDJC alpha does not require the presence of HS4 in the IgH 3' regulatory regionImmunoglobulin gene transcription ceases upon deletion of a distant enhancer.Epigenetic Regulation of Individual Modules of the immunoglobulin heavy chain locus 3' Regulatory Region.Replication and subnuclear location dynamics of the immunoglobulin heavy-chain locus in B-lineage cells.Evidence for physical interaction between the immunoglobulin heavy chain variable region and the 3' regulatory region.The role of CTCF binding sites in the 3' immunoglobulin heavy chain regulatory region.Germline deletion of Igh 3' regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus.Reciprocal homologous recombination in or near antibody VDJ genes.The mouse IgH 3'-enhancer.
P2860
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P2860
Myeloma mutant with a novel 3' flanking region: loss of normal sequence and insertion of repetitive elements leads to decreased transcription but normal processing of the alpha heavy-chain gene products.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Myeloma mutant with a novel 3' ...... pha heavy-chain gene products.
@en
type
label
Myeloma mutant with a novel 3' ...... pha heavy-chain gene products.
@en
prefLabel
Myeloma mutant with a novel 3' ...... pha heavy-chain gene products.
@en
P2860
P356
P1476
Myeloma mutant with a novel 3' ...... pha heavy-chain gene products.
@en
P2093
P D Gregor
S L Morrison
P2860
P304
P356
10.1128/MCB.6.6.1903
P407
P577
1986-06-01T00:00:00Z