Mitogenic effects of the proto-oncogene and oncogene forms of c-H-ras DNA in human diploid fibroblasts.
about
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signalingAn overexpressed gene transcript in senescent and quiescent human fibroblasts encoding a novel protein in the epidermal growth factor-like repeat family stimulates DNA synthesisAn activated c-Ha-ras allele blocks the induction of muscle-specific genes whose expression is contingent on mitogen withdrawal.Reversal of human cellular senescence: roles of the p53 and p16 pathways.Targeting of the rasT24 oncogene to the proximal convoluted tubules in transgenic mice results in hyperplasia and polycystic kidneysExpression of c-fos and AP-1 activity in senescent human fibroblasts is not sufficient for DNA synthesisTransgenic mice carrying the mouse mammary tumor virus ras fusion gene: distinct effects in various tissues.Differential expression of the ras gene family in mice.The ras-like yeast YPT1 gene is itself essential for growth, sporulation, and starvation response.Senescent cells fail to express cdc2, cycA, and cycB in response to mitogen stimulation.Control of myogenic differentiation by cellular oncogenes.MRG15 activates the cdc2 promoter via histone acetylation in human cells.Chronic NF-kappaB activation delays RasV12-induced premature senescence of human fibroblasts by suppressing the DNA damage checkpoint response.
P2860
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P2860
Mitogenic effects of the proto-oncogene and oncogene forms of c-H-ras DNA in human diploid fibroblasts.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Mitogenic effects of the proto ...... in human diploid fibroblasts.
@en
type
label
Mitogenic effects of the proto ...... in human diploid fibroblasts.
@en
prefLabel
Mitogenic effects of the proto ...... in human diploid fibroblasts.
@en
P2093
P2860
P356
P1476
Mitogenic effects of the proto ...... in human diploid fibroblasts.
@en
P2093
C K Lumpkin
J E Knepper
O M Pereira-Smith
P2860
P304
P356
10.1128/MCB.6.8.2990
P407
P577
1986-08-01T00:00:00Z