AAV-based gene therapy prevents neuropathology and results in normal cognitive development in the hyperargininemic mouse.
about
Inducible arginase 1 deficiency in mice leads to hyperargininemia and altered amino acid metabolismStrategies to rescue the consequences of inducible arginase-1 deficiency in miceProof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 DeficiencyMinimal ureagenesis is necessary for survival in the murine model of hyperargininemia treated by AAV-based gene therapy.Myocyte-mediated arginase expression controls hyperargininemia but not hyperammonemia in arginase-deficient mice.Rescue of the Functional Alterations of Motor Cortical Circuits in Arginase Deficiency by Neonatal Gene Therapy.Lethal phenotype in conditional late-onset arginase 1 deficiency in the mouse.Liver-specific knockout of arginase-1 leads to a profound phenotype similar to inducible whole body arginase-1 deficiency.Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells.Possible sources and functions of L-homoarginine in the brain: review of the literature and own findings.Arginase-1 deficiency.A Novel Pathway for Metabolism of the Cardiovascular Risk Factor Homoarginine by alanine:glyoxylate aminotransferase 2.Delivery of glutamine synthetase gene by baculovirus vectors: a proof of concept for the treatment of acute hyperammonemia.
P2860
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P2860
AAV-based gene therapy prevents neuropathology and results in normal cognitive development in the hyperargininemic mouse.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
AAV-based gene therapy prevent ...... in the hyperargininemic mouse.
@en
type
label
AAV-based gene therapy prevent ...... in the hyperargininemic mouse.
@en
prefLabel
AAV-based gene therapy prevent ...... in the hyperargininemic mouse.
@en
P2093
P2860
P356
P1433
P1476
AAV-based gene therapy prevent ...... in the hyperargininemic mouse.
@en
P2093
B Marescau
G S Lipshutz
L Schlichting
N Rozengurt
R Bhargava
P2860
P2888
P304
P356
10.1038/GT.2012.99
P577
2013-02-07T00:00:00Z
P5875
P6179
1019029053