Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells.
about
Historical perspectives on tumor necrosis factor and its superfamily: 25 years later, a golden journey4-1BB Agonists: Multi-Potent Potentiators of Tumor ImmunityReverse signaling through the co-stimulatory ligand, CD137L, as a critical mediator of sterile inflammationExpression of 4-1BB and 4-1BBL in thymocytes during thymus regenerationAgonistic Anti-CD137 Monoclonal Antibody Treatment Induces CD11bGr-1 Myeloid-derived Suppressor Cells.Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8(+) T cellsNovel transmembrane protein 126A (TMEM126A) couples with CD137L reverse signals in myeloid cells.Regulation of granulocyte and macrophage populations of murine bone marrow cells by G-CSF and CD137 proteinCD137 expression is induced by Epstein-Barr virus infection through LMP1 in T or NK cells and mediates survival promoting signals.4-1BB ligand activates bystander dendritic cells to enhance immunization in transCD137 is induced by the CD40 signal on chronic lymphocytic leukemia B cells and transduces the survival signal via NF-κB activationNitric oxide modulates TGF-beta-directive signals to suppress Foxp3+ regulatory T cell differentiation and potentiate Th1 development.Recombinant TAT-CD137 Ligand Cytoplasmic Domain Fusion Protein Induces the Production of IL-6 and TNF-α in Peritoneal MacrophagesReverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation.Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb.Amelioration of Japanese encephalitis by blockage of 4-1BB signaling is coupled to divergent enhancement of type I/II IFN responses and Ly-6C(hi) monocyte differentiation.Hypoxia-induced soluble CD137 in malignant cells blocks CD137L-costimulation as an immune escape mechanism.4-1BB functions as a survival factor in dendritic cells.CD137 ligand reverse signaling skews hematopoiesis towards myelopoiesis during aging.Hypercostimulation through 4-1BB distorts homeostasis of immune cells.The role of TNF superfamily members in T-cell function and diseases.4-1BB signaling beyond T cellsT-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy.The TNF family in T cell differentiation and function--unanswered questions and future directions.Regulation of myelopoiesis by CD137L signaling.Is CD137 Ligand (CD137L) Signaling a Fine Tuner of Immune Responses?ATVB Distinguished Scientist Award: How Costimulatory and Coinhibitory Pathways Shape Atherosclerosis.CD137 ligand-mediated reverse signals increase cell viability and cytokine expression in murine myeloid cells: involvement of mTOR/p70S6 kinase and Akt.In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb.Genetic characterization of bovine viral diarrhea virus strains in Beijing, China and innate immune responses of peripheral blood mononuclear cells in persistently infected dairy cattle.Cutting edge: 4-1BB controls regulatory activity in dendritic cells through promoting optimal expression of retinal dehydrogenaseEnhanced antitumor effects of a dendritic cell vaccine transfected with gastric cancer cell total RNA carrying the 4-1BBL gene in vitro.Functional expression of CD137 (4-1BB) on T helper follicular cells.CD137-CD137 Ligand Interactions in Inflammation.4-1BB ligand signaling to T cells limits T cell activation.CD137 ligand signaling enhances myelopoiesis during infections.Improved Cytotoxic T Lymphocyte Responses to Vaccination with Porcine Reproductive and Respiratory Syndrome Virus in 4-1BB Transgenic Pigs.CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice.The role of soluble and cell-surface expressed 4-1BB ligand in patients with malignant hemopoietic disorders.Molecular Mechanisms of T Cells Activation by Dendritic Cells in Autoimmune Diseases
P2860
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P2860
Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Identification of regulatory f ...... evelopment of dendritic cells.
@en
type
label
Identification of regulatory f ...... evelopment of dendritic cells.
@en
prefLabel
Identification of regulatory f ...... evelopment of dendritic cells.
@en
P2093
P2860
P356
P1433
P1476
Identification of regulatory f ...... development of dendritic cells
@en
P2093
Byoung S Kwon
Hilde Cheroutre
Michael Croft
Robert S Mittler
Seung-Woo Lee
P2860
P304
P356
10.1038/NI.1632
P407
P577
2008-07-06T00:00:00Z