Autophagy-related gene 12 (ATG12) is a novel determinant of primary resistance to HER2-targeted therapies: utility of transcriptome analysis of the autophagy interactome to guide breast cancer treatment.
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Autophagy and Apoptotic Crosstalk: Mechanism of Therapeutic Resistance in HER2-Positive Breast CancerCitrate synthase expression affects tumor phenotype and drug resistance in human ovarian carcinomamiR-23b-3p regulates the chemoresistance of gastric cancer cells by targeting ATG12 and HMGB2Prospective neoadjuvant analysis of PET imaging and mechanisms of resistance to Trastuzumab shows role of HIF1 and autophagy.Autophagy inhibitor facilitates gefitinib sensitivity in vitro and in vivo by activating mitochondrial apoptosis in triple negative breast cancer.STAT3 down regulates LC3 to inhibit autophagy and pancreatic cancer cell growth.Hexokinase II inhibitor, 3-BrPA induced autophagy by stimulating ROS formation in human breast cancer cellsTargeting autophagy in breast cancer.Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention.Combining AKT inhibition with chloroquine and gefitinib prevents compensatory autophagy and induces cell death in EGFR mutated NSCLC cells.Regulation of cell survival by HUNK mediates breast cancer resistance to HER2 inhibitors.Chloroquine enhances gefitinib cytotoxicity in gefitinib-resistant nonsmall cell lung cancer cells.PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2(+) breast cancer cells by inducing Bim.Role of autophagy and lysosomal drug sequestration in acquired resistance to doxorubicin in MCF-7 cellsCancer stem cell-driven efficacy of trastuzumab (Herceptin): towards a reclassification of clinically HER2-positive breast carcinomas.MiR-200b regulates autophagy associated with chemoresistance in human lung adenocarcinomaThe anti-malarial chloroquine overcomes primary resistance and restores sensitivity to trastuzumab in HER2-positive breast cancerPotent antitumor activity of oncolytic adenovirus expressing Beclin-1 via induction of autophagic cell death in leukemiaThe autophagy inhibitor verteporfin moderately enhances the antitumor activity of gemcitabine in a pancreatic ductal adenocarcinoma model.A Tumor initiating cell-enriched prognostic signature for HER2+:ERα- breast cancer; rationale, new features, controversies and future directionsAccumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5.Increased ATG5-ATG12 in hepatitis B virus-associated hepatocellular carcinoma and their role in apoptosis.Neratinib overcomes trastuzumab resistance in HER2 amplified breast cancer.HER4 expression status correlates with improved outcome in both neoadjuvant and adjuvant Trastuzumab treated invasive breast carcinoma.Lapatinib induces p27(Kip1)-dependent G₁ arrest through both transcriptional and post-translational mechanismsSrc and CXCR4 are involved in the invasiveness of breast cancer cells with acquired resistance to lapatinib.Identification of breast cancer cell subtypes sensitive to ATG4B inhibition.Lapatinib resistance in HER2+ cancers: latest findings and new concepts on molecular mechanisms.Acquired resistance to metformin in breast cancer cells triggers transcriptome reprogramming toward a degradome-related metastatic stem-like profile.A comparative analysis of in vitro toxicity of diesel exhaust particles from combustion of 1st- and 2nd-generation biodiesel fuels in relation to their physicochemical properties-the FuelHealth project.Targeting protein quality control pathways in breast cancer.Long noncoding RNA MALAT1 regulates autophagy associated chemoresistance via miR-23b-3p sequestration in gastric cancer.Potentially Functional variants of ATG16L2 predict radiation pneumonitis and outcomes in patients with non-small cell lung cancer after definitive radiotherapy.The cucurbitacins D, E, and I from Ecballium elaterium (L.) upregulate the LC3 gene and induce cell-cycle arrest in human gastric cancer cell line AGS.Autophagy flux inhibition augments gastric cancer resistance to the anti-human epidermal growth factor receptor 2 antibody trastuzumab.
P2860
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P2860
Autophagy-related gene 12 (ATG12) is a novel determinant of primary resistance to HER2-targeted therapies: utility of transcriptome analysis of the autophagy interactome to guide breast cancer treatment.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Autophagy-related gene 12 (ATG ...... guide breast cancer treatment.
@en
type
label
Autophagy-related gene 12 (ATG ...... guide breast cancer treatment.
@en
prefLabel
Autophagy-related gene 12 (ATG ...... guide breast cancer treatment.
@en
P2093
P2860
P356
P1433
P1476
Autophagy-related gene 12 (ATG ...... guide breast cancer treatment.
@en
P2093
Alejandro Vazquez-Martin
Ander Urruticoechea
Bruna Corominas-Faja
Cristina Oliveras-Ferraros
Javier A Menendez
Sílvia Cufí
P2860
P304
P356
10.18632/ONCOTARGET.742
P407
P577
2012-12-01T00:00:00Z