The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein.
about
La FAM fatale: USP9X in development and diseaseSystemic restoration of UBA1 ameliorates disease in spinal muscular atrophyThe role of post-translational modifications in fine-tuning BLM helicase function during DNA repairNew classes of mind bomb-interacting proteins identified from yeast two-hybrid screens.Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth.CNS uptake of bortezomib is enhanced by P-glycoprotein inhibition: implications for spinal muscular atrophyMonoubiquitination of survival motor neuron regulates its cellular localization and Cajal body integrity.ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in miceWorming forward: amyotrophic lateral sclerosis toxicity mechanisms and genetic interactions in Caenorhabditis elegans.Towards an understanding of regulating Cajal body activity by protein modification.Structure and function of the Mind bomb E3 ligase in the context of Notch signal transduction.Epb41l5 competes with Delta as a substrate for Mib1 to coordinate specification and differentiation of neurons.RNA-seq reveals transcriptome changes in goats following myostatin gene knockout.Lysine-Less Variants of Spinal Muscular Atrophy SMN and SMNΔ7 Proteins Are Degraded by the Proteasome Pathway.Self-oligomerization regulates stability of survival motor neuron protein isoforms by sequestering an SCFSlmb degron.CBP-mediated SMN acetylation modulates Cajal body biogenesis and the cytoplasmic targeting of SMN.MIB-1 Is Required for Spermatogenesis and Facilitates LIN-12 and GLP-1 Activity in Caenorhabditis elegans.Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypesUBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy
P2860
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P2860
The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The E3 ubiquitin ligase mind b ...... vival of motor neuron protein.
@en
type
label
The E3 ubiquitin ligase mind b ...... vival of motor neuron protein.
@en
prefLabel
The E3 ubiquitin ligase mind b ...... vival of motor neuron protein.
@en
P2093
P2860
P921
P356
P1476
The E3 ubiquitin ligase mind b ...... vival of motor neuron protein.
@en
P2093
Ajay Chitnis
Anne C Hart
Barbara Terzic
Barrington G Burnett
Casey Cable
Deborah Y Kwon
Kenneth H Fischbeck
Maria Dimitriadi
P2860
P304
P356
10.1091/MBC.E13-01-0042
P577
2013-04-24T00:00:00Z