Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism.
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Dysregulation of histone acetyltransferases and deacetylases in cardiovascular diseasesHDAC and HDAC Inhibitor: From Cancer to Cardiovascular DiseasesEpigenetic modulation as a therapeutic approach for pulmonary arterial hypertensionThe adventitia: essential regulator of vascular wall structure and functionRight ventricular adaptation and failure in pulmonary arterial hypertension.The emerging role of epigenetics in pulmonary arterial hypertension: an important avenue for clinical trials (2015 Grover Conference Series)Emerging roles for histone deacetylases in pulmonary hypertension and right ventricular remodeling (2013 Grover Conference series)Acetyl-lysine erasers and readers in the control of pulmonary hypertension and right ventricular hypertrophyHuman GRK4γ142V Variant Promotes Angiotensin II Type I Receptor-Mediated Hypertension via Renal Histone Deacetylase Type 1 Inhibition.Endoplasmic reticulum stress effector CCAAT/enhancer-binding protein homologous protein (CHOP) regulates chronic kidney disease-induced vascular calcification.Selective inhibition of class I but not class IIb histone deacetylases exerts cardiac protection from ischemia reperfusion.Expression of Class I and Class II a/b Histone Deacetylase is Dysregulated in Hypertensive Animal Models.HDAC9 is an epigenetic repressor of kidney angiotensinogen establishing a sex differenceRole of epigenetics in pulmonary hypertensionThe cancer theory of pulmonary arterial hypertension.Epigenetic modifications: basic mechanisms and role in cardiovascular disease (2013 Grover Conference series).MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblastsConsuming a Western diet for two weeks suppresses fetal genes in mouse hearts.PKG-1α leucine zipper domain defect increases pulmonary vascular tone: implications in hypoxic pulmonary hypertension.Pharmacologic treatments for pulmonary hypertension: exploring pharmacogenomicsClass I HDAC imaging using [ (3)H]CI-994 autoradiographyBlocking the class I histone deacetylase ameliorates renal fibrosis and inhibits renal fibroblast activation via modulating TGF-beta and EGFR signalingTubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy.Restoration of impaired endothelial myocyte enhancer factor 2 function rescues pulmonary arterial hypertension.The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes.Estradiol inhibits Th17 cell differentiation through inhibition of RORγT transcription by recruiting the ERα/REA complex to estrogen response elements of the RORγT promoter.Inhibition of class I histone deacetylase activity represses matrix metalloproteinase-2 and -9 expression and preserves LV function postmyocardial infarction.The Histone Deacetylase Inhibitor Vaproic Acid Induces Cell Growth Arrest in Hepatocellular Carcinoma Cells via Suppressing Notch Signaling.IGF-1 signaling in neonatal hypoxia-induced pulmonary hypertension: Role of epigenetic regulation.HDACs Regulate miR-133a Expression in Pressure Overload-Induced Cardiac Fibrosis.Pulmonary artery smooth muscle cell proliferation and migration in fetal lambs acclimatized to high-altitude long-term hypoxia: role of histone acetylationNovel therapeutic approaches to preserve the right ventricle.Genetic ablation of interleukin-18 does not attenuate hypobaric hypoxia-induced right ventricular hypertrophyMetabolic reprogramming and inflammation act in concert to control vascular remodeling in hypoxic pulmonary hypertension.Reciprocal regulation of RORγt acetylation and function by p300 and HDAC1.Integrating molecular genetics and systems approaches to pulmonary vascular diseases.Histone deacetylation contributes to low extracellular superoxide dismutase expression in human idiopathic pulmonary arterial hypertension.A class of their own: exploring the nondeacetylase roles of class IIa HDACs in cardiovascular diseaseRole of histone deacetylases in regulation of phenotype of ovine newborn pulmonary arterial smooth muscle cells.Transcription factors, transcriptional coregulators, and epigenetic modulation in the control of pulmonary vascular cell phenotype: therapeutic implications for pulmonary hypertension (2015 Grover Conference series).
P2860
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P2860
Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Selective class I histone deac ...... n antiproliferative mechanism.
@en
type
label
Selective class I histone deac ...... n antiproliferative mechanism.
@en
prefLabel
Selective class I histone deac ...... n antiproliferative mechanism.
@en
P2093
P2860
P1433
P1476
Selective class I histone deac ...... n antiproliferative mechanism.
@en
P2093
Adil Anwar
David C Irwin
Douglas D Lemon
Julie Harral
Kim Demos-Davies
Kurt R Stenmark
Maria A Cavasin
Mary C M Weiser-Evans
Michael E Yeager
P2860
P304
P356
10.1161/CIRCRESAHA.111.258426
P50
P577
2012-01-26T00:00:00Z