Exposure to the selective kappa-opioid receptor agonist salvinorin A modulates the behavioral and molecular effects of cocaine in rats. - Wikidata - awgldk - TriplyDB

Exposure to the selective kappa-opioid receptor agonist salvinorin A modulates the behavioral and molecular effects of cocaine in rats.

Exposure to the selective kappa-opioid receptor agonist salvinorin A modulates the behavioral and molecular effects of cocaine in rats.

http://www.wikidata.org/entity/Q36930731

about

Kappa-opioid ligands in the study and treatment of mood disorders Sex Differences in Kappa Opioid Receptor Function and Their Potential Impact on Addiction Drug withdrawal conceptualized as a stressor.Kappa Opioids, Salvinorin A and Major Depressive Disorder Salvinorin A analogs as probes in opioid pharmacology.Effects of kappa opioid receptors on conditioned place aversion and social interaction in males and females Anatomically dissociable effects of dopamine D1 receptor agonists on reward and relief of withdrawal in morphine-dependent rats.The role of kappa-opioid receptor activation in mediating antinociception and addiction.Salvinorin A analogs and other κ-opioid receptor compounds as treatments for cocaine abuse.Effect of kappa-opioid receptor agonists U69593, U50488H, spiradoline and salvinorin A on cocaine-induced drug-seeking in rats.The Nociceptin Receptor as an Emerging Molecular Target for Cocaine Addiction Synthetic studies of neoclerodane diterpenes from Salvia divinorum: role of the furan in affinity for opioid receptors Learning and memory impairment induced by salvinorin A, the principal ingredient of Salvia divinorum, in wistar rats.Effects of the neuropeptide S receptor antagonist RTI-118 on abuse-related facilitation of intracranial self-stimulation produced by cocaine and methylenedioxypyrovalerone (MDPV) in rats.Opioid receptor probes derived from cycloaddition of the hallucinogen natural product salvinorin A.Pharmacology and anti-addiction effects of the novel κ opioid receptor agonist Mesyl Sal B, a potent and long-acting analogue of salvinorin A Repeated exposure to the κ-opioid receptor agonist salvinorin A modulates extracellular signal-regulated kinase and reward sensitivity.Social defeat stress-induced sensitization and escalated cocaine self-administration: the role of ERK signaling in the rat ventral tegmental area.Sex differences in sensitivity to the depressive-like effects of the kappa opioid receptor agonist U-50488 in rats.Effects of peripherally restricted κ opioid receptor agonists on pain-related stimulation and depression of behavior in rats A single injection of a novel κ opioid receptor agonist salvinorin A attenuates the expression of cocaine-induced behavioral sensitization in rats.The Aversive Agent Lithium Chloride Suppresses Phasic Dopamine Release Through Central GLP-1 Receptors.Relative Timing Between Kappa Opioid Receptor Activation and Cocaine Determines the Impact on Reward and Dopamine Release Nucleus Accumbens AMPA Receptors Are Necessary for Morphine-Withdrawal-Induced Negative-Affective States in Rats The kappa-opioid agonist U69,593 blocks cocaine-induced enhancement of brain stimulation reward.Natural products as tools for neuroscience: discovery and development of novel agents to treat drug abuse The 2-methoxy methyl analogue of salvinorin A attenuates cocaine-induced drug seeking and sucrose reinforcements in rats.New therapeutic potential for psychoactive natural products.The dynorphin/κ-opioid receptor system and its role in psychiatric disorders.Salvia divinorum: from Mazatec medicinal and hallucinogenic plant to emerging recreational drug.Salvia divinorum: An overview of the usage, misuse, and addiction processes.Clerodane diterpenes: sources, structures, and biological activities.Modulation of serotonin transporter function by kappa-opioid receptor ligands.Kappa opioid receptor-mediated dysregulation of gamma-aminobutyric acidergic transmission in the central amygdala in cocaine addiction.Synergistic blockade of alcohol escalation drinking in mice by a combination of novel kappa opioid receptor agonist Mesyl Salvinorin B and naltrexone.

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P2860

Exposure to the selective kappa-opioid receptor agonist salvinorin A modulates the behavioral and molecular effects of cocaine in rats.

http://www.wikidata.org/entity/Q36930731

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Exposure to the selective kapp ...... ar effects of cocaine in rats.

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Exposure to the selective kapp ...... ar effects of cocaine in rats.

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Exposure to the selective kapp ...... ar effects of cocaine in rats.

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Neuropsychopharmacology

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Exposure to the selective kapp ...... ar effects of cocaine in rats.

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Bruce M Cohen

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David Potter

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Diane Damez-Werno

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Elena H Chartoff

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William A Carlezon

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P2860

THE EFFECTS OF STRESSFUL LIFE EVENTS ON DEPRESSION

Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist

Studies toward the pharmacophore of salvinorin A, a potent kappa opioid receptor agonist

Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses

U69593, a kappa-opioid agonist, decreases cocaine self-administration and decreases cocaine-produced drug-seeking

Salvinorin A, an active component of the hallucinogenic sage salvia divinorum is a highly efficacious kappa-opioid receptor agonist: structural and functional considerations

Psychotomimesis mediated by kappa opiate receptors

Stress-induced craving and stress response in cocaine dependent individuals

The neural basis of drug craving: an incentive-sensitization theory of addiction

Drug abuse: hedonic homeostatic dysregulation

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2676-2687

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10.1038/SJ.NPP.1301659

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11

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33

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2564810

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