Identification of a gain-of-function mutation of the prolactin receptor in women with benign breast tumors.
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Molecular mechanisms of prolactin and its receptorCrystal Structure of an Affinity-matured Prolactin Complexed to Its Dimerized Receptor Reveals the Topology of Hormone Binding Site 2Prolactin Signaling Stimulates Invasion via Na(+)/H(+) Exchanger NHE1 in T47D Human Breast Cancer CellsLocal prolactin is a target to prevent expansion of basal/stem cells in prostate tumors.Unexploited therapies in breast and prostate cancer: blockade of the prolactin receptor.Ubiquitination-dependent regulation of signaling receptors in cancer.Prolactin inhibits activity of pyruvate kinase M2 to stimulate cell proliferationMutant prolactin receptor and familial hyperprolactinemia.Lactogens and estrogens in breast cancer chemoresistance.Genetic variation in PRL and PRLR, and relationships with serum prolactin levels and breast cancer risk: results from a population-based case-control study in PolandA Residue Quartet in the Extracellular Domain of the Prolactin Receptor Selectively Controls Mitogen-activated Protein Kinase SignalingSignal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer.Investigation of prolactin receptor activation and blockade using time-resolved fluorescence resonance energy transferModeling prolactin actions in breast cancer in vivo: insights from the NRL-PRL mouse.STAT signaling in mammary gland differentiation, cell survival and tumorigenesisImpaired turnover of prolactin receptor contributes to transformation of human breast cells.Functional consequences of prolactin signalling in endothelial cells: a potential link with angiogenesis in pathophysiology?Eliminative signaling by Janus kinases: role in the downregulation of associated receptors.Prolactin--to be reconsidered in canine mammary tumourigenesis?New insights in prolactin: pathological implications.The prolactin receptor as a therapeutic target in human diseases: browsing new potential indications.Truncating Prolactin Receptor Mutations Promote Tumor Growth in Murine Estrogen Receptor-Alpha Mammary Carcinomas.The prolactin receptor: Diverse and emerging roles in pathophysiology.Analysis of Brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit.The prolactin receptor transactivation domain is associated with steroid hormone receptor expression and malignant progression of breast cancer.Cytokine Receptors
P2860
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P2860
Identification of a gain-of-function mutation of the prolactin receptor in women with benign breast tumors.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Identification of a gain-of-fu ...... men with benign breast tumors.
@en
type
label
Identification of a gain-of-fu ...... men with benign breast tumors.
@en
prefLabel
Identification of a gain-of-fu ...... men with benign breast tumors.
@en
P2093
P2860
P356
P1476
Identification of a gain-of-fu ...... men with benign breast tumors.
@en
P2093
Anne Bachelot
Benign Breast Diseases Study Group
Carine Courtillot
Chidi Mestayer
Frédérique Kuttenn
Jean-Baptiste Jomain
Lilya Harutyunyan
Paul A Kelly
Philippe Touraine
Roman L Bogorad
P2860
P304
14533-14538
P356
10.1073/PNAS.0800685105
P407
P577
2008-09-08T00:00:00Z