Alternative TEL-JAK2 fusions associated with T-cell acute lymphoblastic leukemia and atypical chronic myelogenous leukemia dissected in zebrafish - Wikidata - awgldk - TriplyDB

Alternative TEL-JAK2 fusions associated with T-cell acute lymphoblastic leukemia and atypical chronic myelogenous leukemia dissected in zebrafish

Alternative TEL-JAK2 fusions associated with T-cell acute lymphoblastic leukemia and atypical chronic myelogenous leukemia dissected in zebrafish

http://www.wikidata.org/entity/Q36936510

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Zebrafish Models of Human Leukemia: Technological Advances and Mechanistic Insights Zebrafish as a model for leukemia and other hematopoietic disorders Danio rerio: Small Fish Making a Big Splash in Leukemia Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish.Cytokine Signaling in Tumor Progression.An overview of chronic myeloid leukemia and its animal models.Modeling ETV6-JAK2-induced leukemia: insights from the zebrafish.Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia.ETV6 (TEL1) regulates embryonic hematopoiesis in zebrafish.Modeling Myeloid Malignancies Using Zebrafish.Functional analysis of truncated forms of ETV6.Modeling Leukemogenesis in the Zebrafish Using Genetic and Xenograft Models.

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Alternative TEL-JAK2 fusions associated with T-cell acute lymphoblastic leukemia and atypical chronic myelogenous leukemia dissected in zebrafish

http://www.wikidata.org/entity/Q36936510

description

2012 nî lūn-bûn

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HAEMATOL.2012.064659

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Alternative TEL-JAK2 fusions a ...... eukemia dissected in zebrafish

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Alister C Ward

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Clifford Liongue

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Janani Kumar

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Parisa Rasighaemi

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Sara M N Onnebo

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P2860

TYK2 is a key regulator of the surveillance of B lymphoid tumors

The Jak-Stat pathway in normal and perturbed hematopoiesis

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

A gain-of-function mutation of JAK2 in myeloproliferative disorders

Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders

Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate

In situ hybridization screen in zebrafish for the selection of genes encoding secreted proteins.

TEL-JAK2 transgenic mice develop T-cell leukemia.

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1895-1903

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10.3324/HAEMATOL.2012.064659

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12

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22733019

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