Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyelinase activity.
about
Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivoInduction of membrane ceramides: a novel strategy to interfere with T lymphocyte cytoskeletal reorganisation in viral immunosuppression.Essential roles of neutral ceramidase and sphingosine in mitochondrial dysfunction due to traumatic brain injury.Lyn kinase enhanced hepatic fibrosis by modulating the activation of hepatic stellate cells.Involvement of beta1-integrin up-regulation in basic fibroblast growth factor- and epidermal growth factor-induced proliferation of mouse neuroepithelial cells.Human remyelination promoting antibody inhibits apoptotic signaling and differentiation through Lyn kinase in primary rat oligodendrocytes.c-Abl is an upstream regulator of acid sphingomyelinase in apoptosis induced by inhibition of integrins αvβ3 and αvβ5.Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis.PDGF is required for remyelination-promoting IgM stimulation of oligodendrocyte progenitor cell proliferation.Lyn facilitates glioblastoma cell survival under conditions of nutrient deprivation by promoting autophagy.Targeting SRC in glioblastoma tumors and brain metastases: rationale and preclinical studiesSIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY.Ceramide and mitochondria in ischemia/reperfusion.Glia unglued: how signals from the extracellular matrix regulate the development of myelinating glia.Ceramide and mitochondria in ischemic brain injury.Lipid metabolism, apoptosis and cancer therapy.Recruitment of Lyn from endomembranes to the plasma membrane through calcium-dependent cell-cell interactions upon polarization of inducible Lyn-expressing MDCK cells.Functional characterization of six aspartate (D) recombinant mojastin mutants (r-Moj): A second aspartate amino acid carboxyl to the RGD in r-Moj-D_ peptides is not sufficient to induce apoptosis of SK-Mel-28 cells.Oxidized phosphatidylcholine formation and action in oligodendrocytes.Fyn tyrosine kinase regulates the surface expression of glycosylphosphatidylinositol-linked ephrin via the modulation of sphingomyelin metabolism.Acid sphingomyelinase promotes mitochondrial dysfunction due to glutamate-induced regulated necrosis.Ceramide and Ischemia/Reperfusion Injury.Beta adrenoceptor blockade ameliorates impaired glucose tolerance and alterations of the cerebral ceramide metabolism in an experimental model of ischemic stroke.
P2860
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P2860
Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyelinase activity.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Integrin-associated Lyn kinase ...... cid sphingomyelinase activity.
@en
type
label
Integrin-associated Lyn kinase ...... cid sphingomyelinase activity.
@en
prefLabel
Integrin-associated Lyn kinase ...... cid sphingomyelinase activity.
@en
P2093
P2860
P356
P1476
Integrin-associated Lyn kinase ...... cid sphingomyelinase activity.
@en
P2093
Brian W Wheeler
Daria A Chudakova
Mark S Kindy
Sergei A Novgorodov
Tatyana I Gudz
Youssef H Zeidan
P2860
P304
28806-28816
P356
10.1074/JBC.M803301200
P407
P577
2008-08-05T00:00:00Z