CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells. - Wikidata - awgldk - TriplyDB

CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells.

CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells.

http://www.wikidata.org/entity/Q36946584

about

CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin The Role of Chemokines in Shaping the Balance Between CD4(+) T Cell Subsets and Its Therapeutic Implications in Autoimmune and Cancer Diseases Multiple sclerosis: molecular mechanisms and therapeutic opportunities Control of autoimmune CNS inflammation by astrocytes Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases Extracellular ubiquitin: immune modulator and endogenous opponent of damage-associated molecular pattern molecules Ubiquitin is a versatile scaffold protein for the generation of molecules with de novo binding and advantageous drug-like properties Learning from nature: pregnancy changes the expression of inflammation-related genes in patients with multiple sclerosis.Low-dose methotrexate in sickle-cell disease: a pilot study with rationale borrowed from rheumatoid arthritis.Antigen-specific CD25- Foxp3- IFN-gamma(high) CD4+ T cells restrain the development of experimental allergic encephalomyelitis by suppressing Th17.Alginate encapsulant incorporating CXCL12 supports long-term allo- and xenoislet transplantation without systemic immune suppression.Inhibition of hyaluronan synthesis protects against central nervous system (CNS) autoimmunity and increases CXCL12 expression in the inflamed CNS.Heparanase enhances myeloma progression via CXCL10 downregulation.Cytokine dysregulation in early- and late-term placentas from feline immunodeficiency virus (FIV)-infected cats.N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis.Type 1 regulatory T cells (Tr1) in autoimmunity The CXC chemokine receptor 4 ligands ubiquitin and stromal cell-derived factor-1α function through distinct receptor interactions.Structural determinants of ubiquitin-CXC chemokine receptor 4 interaction.Dual targeting of the chemokine receptors CXCR4 and ACKR3 with novel engineered chemokines.Unexpected Regulatory Role of CCR9 in Regulatory T Cell Development.I-domain-antigen conjugate (IDAC) for delivering antigenic peptides to APC: synthesis, characterization, and in vivo EAE suppression The chemokine, CXCL12, is an independent predictor of poor survival in ovarian cancer.Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility Differential responsiveness of Holstein and Angus dermal fibroblasts to LPS challenge occurs without major differences in the methylome.Touch of chemokines.Xenon triggers pro-inflammatory effects and suppresses the anti-inflammatory response compared to sevoflurane in patients undergoing cardiac surgery.Exogenous schwann cells migrate, remyelinate and promote clinical recovery in experimental auto-immune encephalomyelitis.Initial assessment of the role of CXC chemokine receptor 4 after polytrauma.Subcutaneous Transplantation of Neural Precursor Cells in Experimental Autoimmune Encephalomyelitis Reduces Chemotactic Signals in the Central Nervous System Post-CNS-inflammation expression of CXCL12 promotes the endogenous myelin/neuronal repair capacity following spontaneous recovery from multiple sclerosis-like disease Inhibition of CXCL12 signaling attenuates the postischemic immune response and improves functional recovery after stroke.Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease.Identification of gene expression patterns crucially involved in experimental autoimmune encephalomyelitis and multiple sclerosis.Effects of exogenous ubiquitin in a polytrauma model with blunt chest trauma.Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo.Blocking initial infiltration of pioneer CD8(+) T-cells into the CNS via inhibition of SHP-2 ameliorates experimental autoimmune encephalomyelitis in mice.CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis.The multiple faces of CXCL12 (SDF-1alpha) in the regulation of immunity during health and disease.CXCL12 in control of neuroinflammation.The dual roles of inflammatory cytokines and chemokines in the regulation of autoimmune diseases and their clinical implications.

P2860

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P2860

CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells.

http://www.wikidata.org/entity/Q36946584

description

2008 nî lūn-bûn

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CXCL12 (SDF-1alpha) suppresses ...... n-specific regulatory T cells.

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Journal of Experimental Medicine

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CXCL12 (SDF-1alpha) suppresses ...... n-specific regulatory T cells.

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P2093

Gizi Wildbaum

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Moran Meiron

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Nathan Karin

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Rachel Anunu

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Yaniv Zohar

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P2860

Involvement of chemokine receptors in breast cancer metastasis

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage

Plasmid DNA encoding IFN-gamma-inducible protein 10 redirects antigen-specific T cell polarization and suppresses experimental autoimmune encephalomyelitis

Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

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10.1084/JEM.20080730

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11

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205

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18852294

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2571938

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