Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2.
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A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexesInternational Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel familyAutosomal dominant polycystic kidney disease: the last 3 yearsNew and notable ion-channels in the sarcoplasmic/endoplasmic reticulum: do they support the process of intracellular Ca(2+) release?Polycystic liver diseases: advanced insights into the molecular mechanismsA genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formationMolecular advances in autosomal dominant polycystic kidney disease.Polycystin-2 activation by inositol 1,4,5-trisphosphate-induced Ca2+ release requires its direct association with the inositol 1,4,5-trisphosphate receptor in a signaling microdomain.Modulation of the secretory pathway rescues zebrafish polycystic kidney disease pathology.TRP channels of intracellular membranesTreatment strategies and clinical trial design in ADPKDAtomic force microscopy reveals the alternating subunit arrangement of the TRPP2-TRPV4 heterotetramer.VAMP-2, SNAP-25A/B and syntaxin-1 in glutamatergic and GABAergic synapses of the rat cerebellar cortex.Valosin-containing protein-interacting membrane protein (VIMP) links the endoplasmic reticulum with microtubules in concert with cytoskeleton-linking membrane protein (CLIMP)-63ERK1/2-dependent vascular endothelial growth factor signaling sustains cyst growth in polycystin-2 defective mice.Aurora A kinase activity influences calcium signaling in kidney cells.Altered trafficking and stability of polycystins underlie polycystic kidney disease.The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.Polycystin-1, 2, and STIM1 interact with IP(3)R to modulate ER Ca release through the PI3K/Akt pathwaySec63 and Xbp1 regulate IRE1α activity and polycystic disease severity.Vasopressin and disruption of calcium signalling in polycystic kidney disease.Polycystic liver diseases: congenital disorders of cholangiocyte signalingMolecular and cellular pathogenesis of autosomal dominant polycystic kidney disease.Polycystins and cellular Ca2+ signaling.TRP channels.Strategies targeting cAMP signaling in the treatment of polycystic kidney disease.Rare benign tumors of the liver: still rare?Polycystins and partners: proposed role in mechanosensitivity.The transient receptor potential channels TRPP2 and TRPC1 form a heterotetramer with a 2:2 stoichiometry and an alternating subunit arrangement.Mono-ubiquitination of syntaxin 3 leads to retrieval from the basolateral plasma membrane and facilitates cargo recruitment to exosomes.Altered store operated calcium entry increases cyclic 3',5'-adenosine monophosphate production and extracellular signal-regulated kinases 1 and 2 phosphorylation in polycystin-2-defective cholangiocytes.Posttranslational regulation of polycystin-2 protein expression as a novel mechanism of cholangiocyte reaction and repair from biliary damage.Adenylyl cyclase 5 links changes in calcium homeostasis to cAMP-dependent cyst growth in polycystic liver disease.COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathways
P2860
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P2860
Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Syntaxin 5 regulates the endop ...... se properties of polycystin-2.
@en
type
label
Syntaxin 5 regulates the endop ...... se properties of polycystin-2.
@en
prefLabel
Syntaxin 5 regulates the endop ...... se properties of polycystin-2.
@en
P2093
P2860
P356
P1476
Syntaxin 5 regulates the endop ...... se properties of polycystin-2.
@en
P2093
Barbara E Ehrlich
Chi-un Choe
Dayne Y Okuhara
Georgia I Anyatonwu
Stefan Somlo
Yoshiko Maeda
Zhiheng Yu
P2860
P304
15920-15925
P356
10.1073/PNAS.0805062105
P407
P577
2008-10-03T00:00:00Z