Benzyl isothiocyanate targets mitochondrial respiratory chain to trigger reactive oxygen species-dependent apoptosis in human breast cancer cells.
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Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cellsRedox-directed cancer therapeutics: molecular mechanisms and opportunitiesCancer chemoprevention with dietary isothiocyanates mature for clinical translational researchBenzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells.Targeting beta-catenin signaling to induce apoptosis in human breast cancer cells by z-guggulsterone and Gugulipid extract of Ayurvedic medicine plant Commiphora mukul.Phenethyl isothiocyanate sensitizes androgen-independent human prostate cancer cells to docetaxel-induced apoptosis in vitro and in vivo.Inhibition of human breast cancer xenograft growth by cruciferous vegetable constituent benzyl isothiocyanateBenzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human ostep53-Independent apoptosis by benzyl isothiocyanate in human breast cancer cells is mediated by suppression of XIAP expressionCelastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells.Role of mitochondrial electron transport chain complexes in capsaicin mediated oxidative stress leading to apoptosis in pancreatic cancer cells.Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species.Critical role of p53 upregulated modulator of apoptosis in benzyl isothiocyanate-induced apoptotic cell deathBenzyl isothiocyanate causes FoxO1-mediated autophagic death in human breast cancer cells.Differential response of normal (PrEC) and cancerous human prostate cells (PC-3) to phenethyl isothiocyanate-mediated changes in expression of antioxidant defense genes.Role of Bim in diallyl trisulfide-induced cytotoxicity in human cancer cells.Isothiocyanates inhibit proteasome activity and proliferation of multiple myeloma cells.Reactive oxygen species-dependent apoptosis by gugulipid extract of Ayurvedic medicine plant Commiphora mukul in human prostate cancer cells is regulated by c-Jun N-terminal kinase.Cisplatin in combination with Phenethyl Isothiocyanate (PEITC), a potential new therapeutic strategy for malignant pleural mesothelioma.Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3.Benzyl isothiocyanate inhibits epithelial-mesenchymal transition in cultured and xenografted human breast cancer cellsAnticancer effect of icaritin on human lung cancer cells through inducing S phase cell cycle arrest and apoptosis.Proteins as binding targets of isothiocyanates in cancer prevention.Expression of the platelet-activating factor receptor enhances benzyl isothiocyanate-induced apoptosis in murine and human melanoma cellsGlucosinolate-derived isothiocyanates impact mitochondrial function in fungal cells and elicit an oxidative stress response necessary for growth recoveryNotch2 activation by benzyl isothiocyanate impedes its inhibitory effect on breast cancer cell migrationShort-form RON overexpression augments benzyl isothiocyanate-induced apoptosis in human breast cancer cellsTetrathiomolybdate inhibits mitochondrial complex IV and mediates degradation of hypoxia-inducible factor-1α in cancer cells.Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer CellsTamoxifen regulates cell fate through mitochondrial estrogen receptor beta in breast cancer.Altered energy metabolism in cancer: a unique opportunity for therapeutic intervention.Critical role for reactive oxygen species in apoptosis induction and cell migration inhibition by diallyl trisulfide, a cancer chemopreventive component of garlicSuppression of FOXQ1 in benzyl isothiocyanate-mediated inhibition of epithelial-mesenchymal transition in human breast cancer cells.Dietary chemopreventative benzyl isothiocyanate inhibits breast cancer stem cells in vitro and in vivo.Cellular responses to cancer chemopreventive agent D,L-sulforaphane in human prostate cancer cells are initiated by mitochondrial reactive oxygen species.Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications.Role of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells.Diallyl trisulfide-induced apoptosis in human cancer cells is linked to checkpoint kinase 1-mediated mitotic arrestMitochondrial DNA mutations and breast tumorigenesis.Prevention of mammary carcinogenesis in MMTV-neu mice by cruciferous vegetable constituent benzyl isothiocyanate.
P2860
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P2860
Benzyl isothiocyanate targets mitochondrial respiratory chain to trigger reactive oxygen species-dependent apoptosis in human breast cancer cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Benzyl isothiocyanate targets ...... in human breast cancer cells.
@en
type
label
Benzyl isothiocyanate targets ...... in human breast cancer cells.
@en
prefLabel
Benzyl isothiocyanate targets ...... in human breast cancer cells.
@en
P2093
P2860
P356
P1476
Benzyl isothiocyanate targets ...... in human breast cancer cells.
@en
P2093
Anna A Powolny
Shivendra V Singh
P2860
P304
30151-30163
P356
10.1074/JBC.M802529200
P407
P577
2008-09-03T00:00:00Z