Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4 - Wikidata - awgldk - TriplyDB

Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4

Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4

http://www.wikidata.org/entity/Q36949425

about

The BTB-ZF transcription factor Zbtb20 is driven by Irf4 to promote plasma cell differentiation and longevity.Diffuse large B cell lymphoma derived from nodular lymphocyte predominant Hodgkin lymphoma presents with variable histopathology Germinal center B cell development has distinctly regulated stages completed by disengagement from T cell help Pronounced cohabitation of active immunoglobulin genes from three different chromosomes in transcription factories during maximal antibody synthesis.The murine gammaherpesvirus immediate-early Rta synergizes with IRF4, targeting expression of the viral M1 superantigen to plasma cells The NF-κB genomic landscape in lymphoblastoid B cells.IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell-dependent antigen.Complex interactions of transcription factors in mediating cytokine biology in T cells.Transcription elongation factor ELL2 drives Ig secretory-specific mRNA production and the unfolded protein response The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.The generation of antibody-secreting plasma cells.Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses.Epstein-Barr virus nuclear antigen 3A partially coincides with EBNA3C genome-wide and is tethered to DNA through BATF complexes.Murine gammaherpesvirus M2 protein induction of IRF4 via the NFAT pathway leads to IL-10 expression in B cells A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages.The miR-155-PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation Dynamics of B cells in germinal centres.Mitochondrial function provides instructive signals for activation-induced B-cell fates.The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma.A Network Model to Describe the Terminal Differentiation of B Cells Cell of origin of transformed follicular lymphoma Structural Studies of IRF4 Reveal a Flexible Autoinhibitory Region and a Compact Linker Domain The transcription factor PU.1 promotes alternative macrophage polarization and asthmatic airway inflammation Asymmetric PI3K Signaling Driving Developmental and Regenerative Cell Fate Bifurcation.B Cells, Antibodies, and More.RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals.Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development.Transcriptome Analysis of B Cell Immune Functions in Periodontitis: Mucosal Tissue Responses to the Oral Microbiome in Aging.Reversing endogenous alloreactive B cell GC responses with anti-CD154 or CTLA-4Ig.IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity.Epstein-Barr virus nuclear antigen 3C binds to BATF/IRF4 or SPI1/IRF4 composite sites and recruits Sin3A to repress CDKN2A.Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation Interferon regulatory factor 4 attenuates Notch signaling to suppress the development of chronic lymphocytic leukemia.PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia.Regulation of B cell fate by chronic activity of the IgE B cell receptor.Autoimmune manifestations in aged mice arise from early-life immune dysregulation.Differential requirements for the canonical NF-κB transcription factors c-REL and RELA during the generation and activation of mature B cells.Preconditioned mesenchymal stem cells treat myasthenia gravis in a humanized preclinical model.

P2860

Q33569863-EE6569FE-1FB4-40EE-89DF-AAE59C7BB503 Q33647319-3F73CB85-FA0F-42DF-BA04-749461006201 Q33675647-1FAE5647-BDC3-45AC-8D6C-460E5DCD4123 Q33738021-601CF3F1-6A57-4C20-8C1F-82428B492647 Q34015827-2AEA27F7-B5C6-4774-BA2B-79F2DCD380EC Q34175522-20C7C220-D1D9-433C-8505-8C4F314E44A1 Q34230541-16C8A342-F5EB-49FF-A37C-516B61ADFDB4 Q34240220-B079C4A1-AAF1-4209-87D2-6A58D6B7E874 Q34364860-5244C752-FB17-455E-801D-A0B246C76CE8 Q34375208-6174BCE0-BB3F-47F4-B391-D744D95A45E7 Q34463732-9AE5CC1D-B172-49C7-B404-4E44C8C513CA Q34641823-CD2A644E-A54E-46AD-8CC5-14DEE1D086DA Q34647217-E4359159-0023-4FDE-8E5A-52C9CF5304E8 Q34985686-2DBF69E0-4C4F-499E-99EC-6174F951014D Q35082220-D4948A66-895F-4A58-B4AC-EEBF6DF8A982 Q35104157-ED4F68BD-344E-44D6-8B48-2C98E3E14D67 Q35307418-217A78E3-3A5B-4A24-90AC-1375A1FE8446 Q35446555-0D157C1D-6318-4A1E-A874-C43A9FE4FC13 Q35488455-9B32E34D-9679-43C8-B7B3-53563317878F Q35607281-77108627-CC1F-4611-A6F6-AA1E7BEAD0D3 Q35890025-BC4B8261-C91B-4148-84E1-C9D7F2402174 Q36225164-9D994EBF-C6FB-454F-AEAF-AE6A1872972C Q36282910-263D51FE-4645-49AD-B8C9-76BCE561A004 Q36331430-7BAF9364-0066-4988-BEDD-283198C3D2E4 Q36387132-CB5A7E69-156E-4B45-953E-675E8FA6A074 Q36432935-FA851D4E-5F79-4E12-A82E-627537260028 Q36569363-C5EEE680-04FE-41B4-A96B-35301ECA8498 Q36591114-8E4C2D68-1D6D-4D64-B202-893F14B03731 Q36949937-1D0F1B18-6EBA-4F62-895E-23A3153DA86A Q37100431-8B03F5EF-6D3A-411A-B005-05E92614039B Q37231896-98641211-CBFB-4632-BD5E-D3D29E8A46FA Q37397830-ADF18239-3938-4A45-9944-DFEC5AC2C5D0 Q37474974-525EAF08-994D-4F8C-9CA1-F8C6ABA7000C Q37504890-8B64D6DD-6198-4CBB-9468-D4F4A2E02D42 Q37520159-D3466A28-00A4-4CFD-A38A-52C26883A3C2 Q37528135-F88741F3-24CE-42B9-A24E-B753616A63CE Q37552578-AD2A1AB3-D3DA-4BE5-A2FA-1AC79D61D058 Q37624299-6D2C46B8-9594-45C9-A2F9-C9D0024444AE Q37714249-F9E401AA-8A2E-44C4-B99B-62AEA207A7FE Q37730809-B3019976-4663-4B05-9AC6-F5FF860D6DDD

P2860

Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4

http://www.wikidata.org/entity/Q36949425

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Transcriptional regulation of ...... s by dynamical control of IRF4

@en

type

label

Transcriptional regulation of ...... s by dynamical control of IRF4

@en

prefLabel

Transcriptional regulation of ...... s by dynamical control of IRF4

@en

P1433

Q36949425-0D5A08E5-A2C1-4EEB-BEE2-981EF01F8C6A

P1476

Q36949425-7811F8B8-A82A-43D4-A409-33A85BFF39B1

P2093

Q36949425-091BF0FB-9F92-4670-AAC9-FD522F488B1E

Q36949425-1C1F5A73-7345-427E-A6F3-9A76285CC788

Q36949425-5E798ECD-5D20-46CD-8DED-418C9755B5B7

Q36949425-5EF585FB-D2F2-4A74-9B42-5F6009E4DB89

Q36949425-92CA7CD8-51AC-4BDE-B7EB-44A18FDE5F99

Q36949425-A614529E-E0B0-48CA-8601-E88278EA4DC4

Q36949425-AE56695D-FA0C-4D13-9DC5-87C17F518546

Q36949425-C2117438-AE73-4BC3-A567-427A712F18F6

Q36949425-C9B4A1AD-D8CA-417C-B7A8-E8BCE7325DE8

Q36949425-FABF7C83-BFFB-4BDD-9155-6C3960B448AF

P2860

Q36949425-01C37C41-19C5-46A7-9B05-C89A9CABEAAA

Q36949425-09562A7D-2003-4F65-AFDB-D1C9751A2E7F

Q36949425-1708CCAF-6DA1-4758-837A-28A9E2FF2D75

Q36949425-217BCEAA-B892-4863-B5D2-0D4682B63D24

Q36949425-24465F6D-E47C-4235-8A83-8CFD31630CBC

Q36949425-24CE26B1-5662-4D3B-A70E-0DC16AC259CD

Q36949425-3003C13A-3604-45FA-95E7-B95957BF4026

Q36949425-33B11EF8-05FF-476E-AEA9-1956DEA2E103

Q36949425-3E0E5DAB-F5B5-4762-95C1-78842072BC9D

Q36949425-4C0E7F8B-930C-4AF0-9BF1-94A4D226D4C6

P304

Q36949425-D4E76211-2A06-4DDC-8C1B-729DDAFF351A

P31

Q36949425-084AA1EB-BF96-479A-802F-0C819F90C743

P356

Q36949425-3BA3030D-F8AC-49C6-B0C2-156EAA03F44C

P407

Q36949425-E2403459-07A7-42A4-B1E3-248581A37013

P433

Q36949425-96022466-7CA6-446A-A253-9C10A084F1B2

P478

Q36949425-30C4427E-7647-4BAD-89FC-D74BE43E3B77

P50

Q36949425-5C4600E9-D65C-4DC7-A5FA-005FBF74C4B5

P577

Q36949425-A573A8AD-D903-479F-B8E9-A898D0B4543F

P5875

Q36949425-B3ADAE6E-EA9F-4A5D-8676-C7B74B5B3998

P698

Q36949425-88A42D90-24A4-493E-83E3-F8A5161EB607

P932

Q36949425-C2610074-68F2-4160-AE86-C200AE140386

P356

J.IMMUNI.2013.04.009

P1433

P1476

Transcriptional regulation of ...... s by dynamical control of IRF4

@en

P2093

Aaron R Dinner

http://www.w3.org/2001/XMLSchema#string

Anita S Chong

http://www.w3.org/2001/XMLSchema#string

Harinder Singh

http://www.w3.org/2001/XMLSchema#string

Jianjun Chen

http://www.w3.org/2001/XMLSchema#string

Kyoko Ochiai

http://www.w3.org/2001/XMLSchema#string

Mark Maienschein-Cline

http://www.w3.org/2001/XMLSchema#string

Rebecca Rosenthal

http://www.w3.org/2001/XMLSchema#string

Robert Brink

http://www.w3.org/2001/XMLSchema#string

Roger Sciammas

http://www.w3.org/2001/XMLSchema#string

Ulf Klein

http://www.w3.org/2001/XMLSchema#string

P2860

Assembly requirements of PU.1-Pip (IRF-4) activator complexes: inhibiting function in vivo using fused dimers

Batf coordinates multiple aspects of B and T cell function required for normal antibody responses

A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes

The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells

Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter.

The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response.

Defective B cell receptor-mediated responses in mice lacking the Ets protein, Spi-B.

Discovering transcription factor regulatory targets using gene expression and binding data

Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells.

An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling.

P304

918-929

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.IMMUNI.2013.04.009

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

38

http://www.w3.org/2001/XMLSchema#string

P50

Giorgia Simonetti

P577

2013-05-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

236919402

http://www.w3.org/2001/XMLSchema#string

P698

23684984

http://www.w3.org/2001/XMLSchema#string

P932

3690549

http://www.w3.org/2001/XMLSchema#string