Insights on the mechanisms of Ca(2+) regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y).
about
Diseases associated with leaky hemichannelsFunctional analysis and regulation of purified connexin hemichannelsMotifs in the permeation pathway of connexin channels mediate voltage and Ca (2+) sensingAberrant Cx26 hemichannels and keratitis-ichthyosis-deafness syndrome: insights into syndromic hearing lossKeratitis-ichthyosis-deafness syndrome-associated Cx26 mutants produce nonfunctional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43.Altered inhibition of Cx26 hemichannels by pH and Zn2+ in the A40V mutation associated with keratitis-ichthyosis-deafness syndromeGating of Connexin Channels by transjunctional-voltage: Conformations and models of open and closed states.Divalent regulation and intersubunit interactions of human connexin26 (Cx26) hemichannels.Voltage regulation of connexin channel conductance.The First Extracellular Domain Plays an Important Role in Unitary Channel Conductance of Cx50 Gap Junction Channels.Connexin 26 (GJB2) mutation in an Argentinean patient with keratitis-ichthyosis-deafness (KID) syndrome: a case report.Glutathione release through connexin hemichannels: Implications for chemical modification of pores permeable to large molecules.Connexinopathies: a structural and functional glimpseThe carboxyl terminal residues 220-283 are not required for voltage gating of a chimeric connexin32 hemichannel.Mechanism of gating by calcium in connexin hemichannelsCalcium homeostasis modulator (CALHM) ion channels.A Cell-Based Assay to Assess Hemichannel FunctionGap junction structure: unraveled, but not fully revealed.Altered cellular localization and hemichannel activities of KID syndrome associated connexin26 I30N and D50Y mutations.Structural studies of N-terminal mutants of Connexin 26 and Connexin 32 using (1)H NMR spectroscopy.Charged Residues at the First Transmembrane Region Contribute to the Voltage Dependence of the Slow Gate of Connexins.Calcium binding and voltage gating in Cx46 hemichannels.Permeant-specific gating of connexin 30 hemichannels.Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications.Intramolecular signaling in a cardiac connexin: Role of cytoplasmic domain dimerization.The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels.Roles of aberrant hemichannel activities due to mutant connexin26 in the pathogenesis of KID syndrome
P2860
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P2860
Insights on the mechanisms of Ca(2+) regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y).
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Insights on the mechanisms of ...... pathogenic mutations (D50N/Y).
@en
type
label
Insights on the mechanisms of ...... pathogenic mutations (D50N/Y).
@en
prefLabel
Insights on the mechanisms of ...... pathogenic mutations (D50N/Y).
@en
P2093
P2860
P356
P1476
Insights on the mechanisms of ...... pathogenic mutations (D50N/Y)
@en
P2093
Jorge E Contreras
Jorge Gonzalez
William Lopez
P2860
P356
10.1085/JGP.201210893
P577
2013-07-01T00:00:00Z