Human embryonic stem cells have enhanced repair of multiple forms of DNA damage.
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Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaksAneuploidy in stem cellsUltraviolet Radiation-Induced Skin Aging: The Role of DNA Damage and Oxidative Stress in Epidermal Stem Cell Damage Mediated Skin AgingUnderstanding glioma stem cells: rationale, clinical relevance and therapeutic strategiesChanges in human pluripotent stem cell gene expression after genotoxic stress exposuresDNA repair in human pluripotent stem cells is distinct from that in non-pluripotent human cellsBalancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Repair at single targeted DNA double-strand breaks in pluripotent and differentiated human cellsPorphyrin homeostasis maintained by ABCG2 regulates self-renewal of embryonic stem cellsDNA damage responses in human induced pluripotent stem cells and embryonic stem cells.Radiation-induced bystander effects in cultured human stem cells.Mitochondrial base excision repair assaysHuman pluripotent stem cells have a novel mismatch repair-dependent damage response.Cancer-initiating cells derived from established cervical cell lines exhibit stem-cell markers and increased radioresistance.Unraveling the global microRNAome responses to ionizing radiation in human embryonic stem cells.Metabolic regulation of redox status in stem cells.Enhanced genetic integrity in mouse germ cellsGenome-wide profiling of pluripotent cells reveals a unique molecular signature of human embryonic germ cells.Inhibition of pluripotent stem cell-derived teratoma formation by small moleculesMolecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks.Stem cells: the pursuit of genomic stability.Mismatch and base excision repair proficiency in murine embryonic stem cellsDynamics of the transcriptome response of cultured human embryonic stem cells to ionizing radiation exposure.Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling eventsEffects of oxidative stress on mouse embryonic stem cell proliferation, apoptosis, senescence, and self-renewalHigh glutathione and glutathione peroxidase-2 levels mediate cell-type-specific DNA damage protection in human induced pluripotent stem cellsRegulation of Stem Cell Fate by ROS-mediated Alteration of Metabolism.Genome integrity, stem cells and hyaluronan.The human embryonic stem cell proteome revealed by multidimensional fractionation followed by tandem mass spectrometryHuman embryonic stem cell responses to ionizing radiation exposures: current state of knowledge and future challengesResponses of human embryonic stem cells and their differentiated progeny to ionizing radiation.Genetic stability of pluripotent stem cells during anti-cancer therapiesAssessing the risks of genotoxicity in the therapeutic development of induced pluripotent stem cellsMitochondria in human pluripotent stem cell apoptosis.Targeted deletion of mouse Rad1 leads to deficient cellular DNA damage responses.Pluripotent Stem Cells and DNA Damage Response to Ionizing Radiations.Lessons learned about human stem cell responses to ionizing radiation exposures: a long road still ahead of us.Genetic and epigenetic variations in iPSCs: potential causes and implications for applicationRadiosensitivity of cancer-initiating cells and normal stem cells (or what the Heisenberg uncertainly principle has to do with biology)Human induced pluripotent cells resemble embryonic stem cells demonstrating enhanced levels of DNA repair and efficacy of nonhomologous end-joining.
P2860
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P2860
Human embryonic stem cells have enhanced repair of multiple forms of DNA damage.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Human embryonic stem cells have enhanced repair of multiple forms of DNA damage.
@en
type
label
Human embryonic stem cells have enhanced repair of multiple forms of DNA damage.
@en
prefLabel
Human embryonic stem cells have enhanced repair of multiple forms of DNA damage.
@en
P2093
P2860
P1433
P1476
Human embryonic stem cells have enhanced repair of multiple forms of DNA damage.
@en
P2093
Alexandre Bettencourt Da Cruz
Anna Maria Swistowska
Jae Wan Lee
Mahendra Rao
Nadja C de Souza-Pinto
Su-Ting Liu
Vilhelm A Bohr
Xianmin Zeng
P2860
P304
P356
10.1634/STEMCELLS.2007-1041
P577
2008-06-19T00:00:00Z