Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin
about
Human and great ape red blood cells differ in plasmalogen levels and compositionAlzheimer's disease as homeostatic responses to age-related myelin breakdownCurrent and future pharmacological treatment strategies in X-linked adrenoleukodystrophyAlkyl-glycerol rescues plasmalogen levels and pathology of ether-phospholipid deficient micePlasmalogens rescue neuronal cell death through an activation of AKT and ERK survival signalingOxidative stress and adrenocortical insufficiency.Very long-chain fatty acid accumulation causes lipotoxic response via 5-lipoxygenase in cerebral adrenoleukodystrophy.Oral administration of cytosolic PLA2 inhibitor arachidonyl trifluoromethyl ketone ameliorates cauda equina compression injury in ratsA peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency.Pathomechanisms underlying X-adrenoleukodystrophy: a three-hit hypothesis.Peroxisomal dysfunction in inflammatory childhood white matter disorders: an unexpected contributor to neuropathologyHistone deacetylase inhibitor upregulates peroxisomal fatty acid oxidation and inhibits apoptotic cell death in abcd1-deficient glial cells.HDAC inhibitor SAHA normalizes the levels of VLCFAs in human skin fibroblasts from X-ALD patients and downregulates the expression of proinflammatory cytokines in Abcd1/2-silenced mouse astrocytes.The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesisSilencing of Abcd1 and Abcd2 genes sensitizes astrocytes for inflammation: implication for X-adrenoleukodystrophy.Reduction of lipoxidative load by secretory phospholipase A2 inhibition protects against neurovascular injury following experimental stroke in rat.Myelin proteomics: molecular anatomy of an insulating sheath.Global Changes in Lipid Profiles of Mouse Cortex, Hippocampus, and Hypothalamus Upon p53 Knockout.Peroxisomes: a nexus for lipid metabolism and cellular signaling.Coenzyme-A-Independent Transacylation System; Possible Involvement of Phospholipase A2 in Transacylation.From peroxisomal disorders to common neurodegenerative diseases - the role of ether phospholipids in the nervous system.Adenoviruses-mediated RNA interference targeting cytosolic phospholipase A2α attenuates focal ischemic brain damage in mice.
P2860
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P2860
Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin
@en
type
label
Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin
@en
prefLabel
Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin
@en
P2093
P2860
P1476
Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin
@en
P2093
Inderjit Singh
Jaspreet Singh
Mushfiquddin Khan
P2860
P304
P356
10.1111/J.1471-4159.2008.05513.X
P407
P577
2008-06-07T00:00:00Z