The STAT3 NH2-terminal domain stabilizes enhanceosome assembly by interacting with the p300 bromodomain.
about
The Sin3a repressor complex is a master regulator of STAT transcriptional activityAcetyltransferase p300 regulates NBS1-mediated DNA damage responseThe role of human bromodomains in chromatin biology and gene transcriptionPivotal Importance of STAT3 in Protecting the Heart from Acute and Chronic Stress: New Advancement and Unresolved IssuesProtein lysine acetylation by p300/CBPBromodomains: Translating the words of lysine acetylation into myelin injury and repairGeneration of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia TherapyNovel interactions between NFATc1 (Nuclear Factor of Activated T cells c1) and STAT-3 (Signal Transducer and Activator of Transcription-3) mediate G protein-coupled receptor agonist, thrombin-induced biphasic expression of cyclin D1, with first phasRegulation of signal transducer and activator of transcription 3 enhanceosome formation by apurinic/apyrimidinic endonuclease 1 in hepatic acute phase response.Inducible STAT3 NH2 terminal mono-ubiquitination promotes BRD4 complex formation to regulate apoptosisWriters and readers of histone acetylation: structure, mechanism, and inhibitionInhibition of STAT3 acetylation is associated with angiotesin renal fibrosis in the obstructed kidney.The nuclear factor-kappaB-interleukin-6 signalling pathway mediating vascular inflammation.Plumbagin promotes the generation of astrocytes from rat spinal cord neural progenitors via activation of the transcription factor Stat3.P300-dependent STAT3 acetylation is necessary for angiotensin II-induced pro-fibrotic responses in renal tubular epithelial cells.Deciphering STAT3 signaling in the heart: plasticity and vascular inflammation.BRD4 sustains melanoma proliferation and represents a new target for epigenetic therapyHDAC inhibition and graft versus host diseaseKlotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation.IL-32γ inhibits cancer cell growth through inactivation of NF-κB and STAT3 signals.RelA Ser276 phosphorylation-coupled Lys310 acetylation controls transcriptional elongation of inflammatory cytokines in respiratory syncytial virus infection.High-density P300 enhancers control cell state transitions.Targeting the interleukin-6/Jak/stat pathway in human malignanciesRegulation of STAT signaling by acetylation.Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factorThe IL-6 trans-signaling-STAT3 pathway mediates ECM and cellular proliferation in fibroblasts from hypertrophic scar.Differential STAT3 signaling in the heart: Impact of concurrent signals and oxidative stress.Antitumor activity of IL-32β through the activation of lymphocytes, and the inactivation of NF-κB and STAT3 signalsDancing rhinos in stilettos: The amazing saga of the genomic and nongenomic actions of STAT3 in the heart.Genomic and computational approaches to dissect the mechanisms of STAT3's universal and cell type-specific functions.EP300 Protects from Light-Induced Retinopathy in Zebrafish.Analysis of STAT3 post-translational modifications (PTMs) in human prostate cancer with different Gleason Score.STAT3 signaling in immunity.Deacetylase inhibitors repress STAT5-mediated transcription by interfering with bromodomain and extra-terminal (BET) protein function.Cytokine amplification and macrophage effector functions in aortic inflammation and abdominal aortic aneurysm formation.TNFR2 Stimulation Promotes Mitochondrial Fusion via Stat3- and NF-kB-Dependent Activation of OPA1 Expression.A dynamic interplay of enhancer elements regulates Klf4 expression in naïve pluripotency.Disruption of STAT3-DNMT1 interaction by SH-I-14 induces re-expression of tumor suppressor genes and inhibits growth of triple-negative breast tumor.Roles of HDACs in the Responses of Innate Immune Cells and as Targets in Inflammatory Diseases.Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.
P2860
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P2860
The STAT3 NH2-terminal domain stabilizes enhanceosome assembly by interacting with the p300 bromodomain.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The STAT3 NH2-terminal domain ...... ing with the p300 bromodomain.
@en
type
label
The STAT3 NH2-terminal domain ...... ing with the p300 bromodomain.
@en
prefLabel
The STAT3 NH2-terminal domain ...... ing with the p300 bromodomain.
@en
P2093
P2860
P356
P1476
The STAT3 NH2-terminal domain ...... ting with the p300 bromodomain
@en
P2093
Sutapa Ray
Tieying Hou
P2860
P304
30725-30734
P356
10.1074/JBC.M805941200
P407
P577
2008-09-09T00:00:00Z