Plasminogen mediates the atherogenic effects of macrophage-expressed urokinase and accelerates atherosclerosis in apoE-knockout mice
about
Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low-density lipoprotein.Overexpression of urokinase by plaque macrophages causes histological features of plaque rupture and increases vascular matrix metalloproteinase activity in aged apolipoprotein e-null micePlasminogen promotes macrophage phagocytosis in miceMechanisms of urokinase plasminogen activator (uPA)-mediated atherosclerosis: role of the uPA receptor and S100A8/A9 proteinsReduction of mouse atherosclerosis by urokinase inhibition or with a limited-spectrum matrix metalloproteinase inhibitor.Oxidized phospholipids are present on plasminogen, affect fibrinolysis, and increase following acute myocardial infarction.The annexin A2/S100A10 system in health and disease: emerging paradigmsMacrophage gene expression and foam cell formation are regulated by plasminogen.Enzymatically Modified Low-Density Lipoprotein Promotes Foam Cell Formation in Smooth Muscle Cells via Macropinocytosis and Enhances Receptor-Mediated Uptake of Oxidized Low-Density Lipoprotein.Level of macrophage uPA expression is an important determinant of atherosclerotic lesion growth in Apoe-/- mice.Molecular biology of atherosclerosis.Urokinase-type plasminogen activator deficiency in bone marrow-derived cells augments rupture of angiotensin II-induced abdominal aortic aneurysms.Physiology and pathophysiology of the plasminogen system in the kidney.Plasminogen promotes cholesterol efflux by the ABCA1 pathway.Plasmin induces intercellular adhesion molecule 1 expression in human endothelial cells via nuclear factor-κB/mitogen-activated protein kinases-dependent pathways.TCRβ-expressing macrophages induced by a pathogenic murine malaria correlate with parasite burden and enhanced phagocytic activity
P2860
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P2860
Plasminogen mediates the atherogenic effects of macrophage-expressed urokinase and accelerates atherosclerosis in apoE-knockout mice
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Plasminogen mediates the ather ...... clerosis in apoE-knockout mice
@en
type
label
Plasminogen mediates the ather ...... clerosis in apoE-knockout mice
@en
prefLabel
Plasminogen mediates the ather ...... clerosis in apoE-knockout mice
@en
P2093
P2860
P356
P1476
Plasminogen mediates the ather ...... clerosis in apoE-knockout mice
@en
P2093
Abigail Plawman
April Stempien-Otero
David A Dichek
Jie Hong Hu
Katherine I Slezicki
Michal Kremen
Ranjini Krishnan
P2860
P304
17109-17114
P356
10.1073/PNAS.0808650105
P407
P50
P577
2008-10-28T00:00:00Z