Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus
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Disruption of a Regulatory Network Consisting of Neutrophils and Platelets Fosters Persisting Inflammation in Rheumatic DiseasesResolution of Inflammation: What Controls Its Onset?Do neutrophil extracellular traps contribute to the heightened risk of thrombosis in inflammatory diseases?Miraculous catch by neutrophils NETsCardiovascular disease in lupus: insights and updatesDamage-associated molecular pattern-activated neutrophil extracellular trap exacerbates sterile inflammatory liver injury.Intercellular Interactions as Regulators of NETosisInhibition of NET Release Fails to Reduce Adipose Tissue Inflammation in MiceLactoferrin Suppresses Neutrophil Extracellular Traps Release in InflammationMénage-à-Trois: The Ratio of Bicarbonate to CO2 and the pH Regulate the Capacity of Neutrophils to Form NETsExperimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps.Lupus and proliferative nephritis are PAD4 independent in murine models.Bovine Polymorphonuclear Neutrophils Cast Neutrophil Extracellular Traps against the Abortive Parasite Neospora caninum.Anti-high Mobility Group Box 1 Antibody Ameliorates Albuminuria in MRL/lpr Lupus-Prone Mice.Neutrophil extracellular traps exacerbate Th1-mediated autoimmune responses in rheumatoid arthritis by promoting DC maturation.Neutrophils in the tumor microenvironment: trying to heal the wound that cannot heal.Inflammation and thrombosis in cardiovascular disease.The role of neutrophils and NETosis in autoimmune and renal diseases.Detection of SLE antigens in neutrophil extracellular traps (NETs)Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2Neutrophil extracellular trap-derived enzymes oxidize high-density lipoprotein: an additional proatherogenic mechanism in systemic lupus erythematosus.Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis.Peptidyl arginine deiminase-4 activation exacerbates kidney ischemia-reperfusion injury.Epigenetics of autoantigens: new opportunities for therapy of autoimmune diseases.Developing an irreversible inhibitor of human DDAH-1, an enzyme upregulated in melanoma.Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice.Identification of multiple structurally distinct, nonpeptidic small molecule inhibitors of protein arginine deiminase 3 using a substrate-based fragment methodChemical biology of protein arginine modifications in epigenetic regulationChronic, not acute, skin-specific inflammation promotes thrombosis in psoriasis murine modelsA novel image-based quantitative method for the characterization of NETosis.Neutrophils Regulate Humoral Autoimmunity by Restricting Interferon-γ Production via the Generation of Reactive Oxygen Species.Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.Neutrophil Extracellular Trap-Related Extracellular Histones Cause Vascular Necrosis in Severe GNAt the Bench: Neutrophil extracellular traps (NETs) highlight novel aspects of innate immune system involvement in autoimmune diseases.Chemical Proteomic Platform To Identify Citrullinated ProteinsDetection and identification of protein citrullination in complex biological systemsNeutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease.The assessment of serum-mediated phagocytosis of necrotic material by polymorphonuclear leukocytes to diagnose and predict the clinical features of systemic lupus erythematosus: an observational longitudinal studyDeimination of linker histones links neutrophil extracellular trap release with autoantibodies in systemic autoimmunity.Protein Arginine Methylation and Citrullination in Epigenetic Regulation
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P2860
Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Peptidylarginine deiminase inh ...... culoprotective in murine lupus
@en
Peptidylarginine deiminase inh ...... culoprotective in murine lupus
@en-gb
type
label
Peptidylarginine deiminase inh ...... culoprotective in murine lupus
@en
Peptidylarginine deiminase inh ...... culoprotective in murine lupus
@en-gb
prefLabel
Peptidylarginine deiminase inh ...... culoprotective in murine lupus
@en
Peptidylarginine deiminase inh ...... culoprotective in murine lupus
@en-gb
P2093
P2860
P356
P1476
Peptidylarginine deiminase inh ...... culoprotective in murine lupus
@en
P2093
Alexander A O'Dell
Daniel T Eitzman
Jason S Knight
Jeffrey B Hodgin
Mariana J Kaplan
Paul R Thompson
Srilakshmi Yalavarthi
Wenpu Zhao
P2860
P304
P356
10.1172/JCI67390
P407
P577
2013-06-03T00:00:00Z