Deregulation of apoptotic factors Bcl-xL and Bax confers apoptotic resistance to myeloid-derived suppressor cells and contributes to their persistence in cancer.
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Myeloid-Derived Suppressor Cells: Critical Cells Driving Immune Suppression in the Tumor MicroenvironmentMyeloid-derived suppressor cells in the tumor microenvironment: expect the unexpectedER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosisCeramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytesArsenic trioxide inhibits tumor-induced myeloid-derived suppressor cells and enhances T-cell activity.IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation.Sustained interleukin-1β exposure modulates multiple steps in glucocorticoid receptor signaling, promoting split-resistance to the transactivation of prominent anti-inflammatory genes by glucocorticoidsMMP3-mediated tumor progression is controlled transcriptionally by a novel IRF8-MMP3 interaction.Transcriptional regulation of myeloid-derived suppressor cells.Relevance of Interferon Regulatory Factor-8 Expression in Myeloid-Tumor Interactions.Thapsigargin sensitizes human esophageal cancer to TRAIL-induced apoptosis via AMPK activation.Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progressionCeramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid-derived suppressor cells.Highlights on mechanisms of drugs targeting MDSCs: providing a novel perspective on cancer treatment.An Orthotopic Mouse Model of Spontaneous Breast Cancer Metastasis.Total cellular protein presence of the transcription factor IRF8 does not necessarily correlate with its nuclear presence.The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells.Neonatal myeloid derived suppressor cells show reduced apoptosis and immunosuppressive activity upon infection with Escherichia coli.A Schistosoma japonicum Infection Promotes the Expansion of Myeloid-Derived Suppressor Cells by Activating the JAK/STAT3 Pathway.The dual role of IRF8 in cancer immunosurveillance.The Granulocyte Progenitor Stage Is a Key Target of IRF8-Mediated Regulation of Myeloid-Derived Suppressor Cell Production.SETD1B Activates iNOS Expression in Myeloid-Derived Suppressor Cells.S100A4 Protects Myeloid-Derived Suppressor Cells from Intrinsic Apoptosis via TLR4-ERK1/2 Signaling.S100A4 Protects Myeloid-Derived Suppressor Cells from Intrinsic Apoptosis via TLR4–ERK1/2 Signaling.Pak2 regulates myeloid-derived suppressor cell development in mice
P2860
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P2860
Deregulation of apoptotic factors Bcl-xL and Bax confers apoptotic resistance to myeloid-derived suppressor cells and contributes to their persistence in cancer.
description
2013 nî lūn-bûn
@nan
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
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2013年論文
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2013年论文
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2013年论文
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2013年论文
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name
Deregulation of apoptotic fact ...... o their persistence in cancer.
@en
type
label
Deregulation of apoptotic fact ...... o their persistence in cancer.
@en
prefLabel
Deregulation of apoptotic fact ...... o their persistence in cancer.
@en
P2093
P2860
P356
P1476
Deregulation of apoptotic fact ...... to their persistence in cancer
@en
P2093
Amy V Paschall
Asha Nayak-Kapoor
Dafeng Yang
Jennifer L Waller
Kankana Bardhan
Mary Anne Park
Scott I Abrams
Thomas A Samuel
Xiaolin Hu
P2860
P304
19103-19115
P356
10.1074/JBC.M112.434530
P407
P50
P577
2013-05-15T00:00:00Z