Quantifying the topography of the intrinsic energy landscape of flexible biomolecular recognition
about
Atomistic picture for the folding pathway of a hybrid-1 type human telomeric DNA G-quadruplexConformational frustration in calmodulin-target recognition.Digested disorder: Quarterly intrinsic disorder digest (April-May-June, 2013).Electrostatic forces govern the binding mechanism of intrinsically disordered histone chaperones.SPA-LN: a scoring function of ligand-nucleic acid interactions via optimizing both specificity and affinity.Protein-protein docking: from interaction to interactomePolycation-π interactions are a driving force for molecular recognition by an intrinsically disordered oncoprotein family.PolyUbiquitin chain linkage topology selects the functions from the underlying binding landscapeInterrogating the activities of conformational deformed enzyme by single-molecule fluorescence-magnetic tweezers microscopyCoupled folding and binding with 2D Window-Exchange Umbrella Sampling.Protein recognition and selection through conformational and mutually induced fit.Molecular dynamics simulations and CD spectroscopy reveal hydration-induced unfolding of the intrinsically disordered LEA proteins COR15A and COR15B from Arabidopsis thaliana.Quantifying Nonnative Interactions in the Protein-Folding Free-Energy Landscape.Specificity and affinity quantification of flexible recognition from underlying energy landscape topography.Molecular mechanism of multispecific recognition of Calmodulin through conformational changes.Conformation Dynamics of the Intrinsically Disordered Protein c-Myb with the ff99IDPs Force Field.The free energy landscape in translational science: how can somatic mutations result in constitutive oncogenic activation?Manipulating motions of targeted single cells in solution by an integrated double-ring magnetic tweezers imaging microscope.Effects of flexibility and electrostatic interactions on the coupled binding-folding mechanisms of Chz.core and H2A.z-H2B.Understanding the roles of intrinsic disorder in subunits of hemoglobin and the disease process of sickle cell anemia.Manipulating and probing enzymatic conformational fluctuations and enzyme-substrate interactions by single-molecule FRET-magnetic tweezers microscopy.Optimizing the affinity and specificity of ligand binding with the inclusion of solvation effect.Opposing Intermolecular Tuning of Ca2+ Affinity for Calmodulin by Neurogranin and CaMKII Peptides.Efficient flexible backbone protein-protein docking for challenging targetsQuantifying the Intrinsic Conformation Energy Landscape Topography of Proteins with Large-Scale Open-Closed Transition
P2860
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P2860
Quantifying the topography of the intrinsic energy landscape of flexible biomolecular recognition
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
Quantifying the topography of ...... xible biomolecular recognition
@en
type
label
Quantifying the topography of ...... xible biomolecular recognition
@en
prefLabel
Quantifying the topography of ...... xible biomolecular recognition
@en
P2093
P2860
P356
P1476
Quantifying the topography of ...... xible biomolecular recognition
@en
P2093
P2860
P304
P356
10.1073/PNAS.1220699110
P407
P50
P577
2013-06-10T00:00:00Z