Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter 2 from a helper virus-free herpes simplex virus type 1 vector supports high-level, long-term biochemical and behaviora
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Catecholamine autotoxicity. Implications for pharmacology and therapeutics of Parkinson disease and related disordersPrimary skin fibroblasts as a model of Parkinson's diseaseGenetic enhancement of visual learning by activation of protein kinase C pathways in small groups of rat cortical neuronsHuman gene therapy and imaging in neurological diseases.Enhanced nigrostriatal neuron-specific, long-term expression by using neural-specific promoters in combination with targeted gene transfer by modified helper virus-free HSV-1 vector particles.Improved long-term expression from helper virus-free HSV-1 vectors packaged using combinations of mutated HSV-1 proteins that include the UL13 protein kinase and specific components of the VP16 transcriptional complex.Intra-neuronal vesicular uptake of catecholamines is decreased in patients with Lewy body diseases.Comparison of Monoamine Oxidase Inhibitors in Decreasing Production of the Autotoxic Dopamine Metabolite 3,4-Dihydroxyphenylacetaldehyde in PC12 Cells.Subthalamic hGAD65 gene therapy and striatum TH gene transfer in a Parkinson's disease rat model.HSV-1 amplicon vectors: a promising and versatile tool for gene delivery.Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease.Genetic modification of stem cells for transplantation.Targeting the central nervous system with herpes simplex virus / Sleeping Beauty hybrid amplicon vectors.Gene therapy for the treatment of Parkinson's disease: the nature of the biologics expands the future indicationsAntibody-mediated targeted gene transfer of helper virus-free HSV-1 vectors to rat neocortical neurons that contain either NMDA receptor 2B or 2A subunits.A 16 bp upstream sequence from the rat tyrosine hydroxylase promoter supports long-term expression from a neurofilament promoter, in a helper virus-free HSV-1 vector system.Neurotransmitter release: vacuolar ATPase V0 sector c-subunits in possible gene or cell therapies for Parkinson's, Alzheimer's, and psychiatric diseases.Neurons can be labeled with unique hues by helper virus-free HSV-1 vectors expressing Brainbow.Linking Stress, Catecholamine Autotoxicity, and Allostatic Load with Neurodegenerative Diseases: A Focused Review in Memory of Richard Kvetnansky.The vesicular glutamate transporter-1 upstream promoter and first intron each support glutamatergic-specific expression in rat postrhinal cortex.Genetic labeling of both the axons of transduced, glutamatergic neurons in rat postrhinal cortex and their postsynaptic neurons in other neocortical areas by herpes simplex virus vectors that coexpress an axon-targeted β-galactosidase and wheat germAntibody-mediated targeted gene transfer to NMDA NR1-containing neurons in rat neocortex by helper virus-free HSV-1 vector particles containing a chimeric HSV-1 glycoprotein C-staphylococcus A proteinHerpes Virus Amplicon Vectors.Glutamatergic or GABAergic neuron-specific, long-term expression in neocortical neurons from helper virus-free HSV-1 vectors containing the phosphate-activated glutaminase, vesicular glutamate transporter-1, or glutamic acid decarboxylase promoter.Isolation of an enhancer from the rat tyrosine hydroxylase promoter that supports long-term, neuronal-specific expression from a neurofilament promoter, in a helper virus-free HSV-1 vector system.A helper virus-free HSV-1 vector containing the vesicular glutamate transporter-1 promoter supports expression preferentially in VGLUT1-containing glutamatergic neurons.Overexpression of either lysine-specific demethylase-1 or CLOCK, but not Co-Rest, improves long-term expression from a modified neurofilament promoter, in a helper virus-free HSV-1 vector systemImproved spatial learning in aged rats by genetic activation of protein kinase C in small groups of hippocampal neurons.Dopamine gene therapy for Parkinson's disease in a nonhuman primate without associated dyskinesia.Potential cellular and regenerative approaches for the treatment of Parkinson's disease.Long-term inducible expression in striatal neurons from helper virus-free HSV-1 vectors that contain the tetracycline-inducible promoter system.CaMKII, MAPK, and CREB are coactivated in identified neurons in a neocortical circuit required for performing visual shape discriminations.Characteristic and intermingled neocortical circuits encode different visual object discriminations.Gene Therapy for Parkinson's Disease, An Update.
P2860
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P2860
Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter 2 from a helper virus-free herpes simplex virus type 1 vector supports high-level, long-term biochemical and behaviora
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Coexpression of tyrosine hydro ...... term biochemical and behaviora
@en
type
label
Coexpression of tyrosine hydro ...... term biochemical and behaviora
@en
prefLabel
Coexpression of tyrosine hydro ...... term biochemical and behaviora
@en
P2093
P2860
P356
P1433
P1476
Coexpression of tyrosine hydro ...... term biochemical and behaviora
@en
P2093
Alfred I Geller
Courtney Holmes
David S Goldstein
Guo-Rong Zhang
Josef Pfeilschifter
Lingxin Kong
Qingsheng Gao
Xiaodan Wang
P2860
P304
P356
10.1089/HUM.2004.15.1177
P577
2004-12-01T00:00:00Z