Ceramide starves cells to death by downregulating nutrient transporter proteins - Wikidata - awgldk - TriplyDB

Ceramide starves cells to death by downregulating nutrient transporter proteins

Ceramide starves cells to death by downregulating nutrient transporter proteins

http://www.wikidata.org/entity/Q36971061

about

Trafficking and Functions of Bioactive Sphingolipids: Lessons from Cells and Model Membranes Autophagy paradox and ceramide Lipid modulation of skeletal muscle mass and function Sphingolipids as cell fate regulators in lung development and disease Autophagy regulates sphingolipid levels in the liver Ceramide induced mitophagy and tumor suppression C2-phytoceramide perturbs lipid rafts and cell integrity in Saccharomyces cerevisiae in a sterol-dependent manner PDMP induces rapid changes in vacuole morphology in Arabidopsis root cells.Evidence for the involvement of GD3 ganglioside in autophagosome formation and maturation.Smoking exposure induces human lung endothelial cell adaptation to apoptotic stress.Global metabolomic analysis of human saliva and plasma from healthy and diabetic subjects, with and without periodontal disease New role for EMD (emerin), a key inner nuclear membrane protein, as an enhancer of autophagosome formation in the C16-ceramide autophagy pathway The yeast sphingolipid signaling landscape.Attacking the supply wagons to starve cancer cells to death.Small-molecule regulators of autophagy and their potential therapeutic applications.Synergistic interactions between heregulin and peroxisome proliferator-activated receptor-gamma (PPARgamma) agonist in breast cancer cells.C6-ceramide nanoliposomes target the Warburg effect in chronic lymphocytic leukemia.Autophagy in the light of sphingolipid metabolism Ceramides as modulators of cellular and whole-body metabolism Ethyl pyruvate preserves IGF-I sensitivity toward mTOR substrates and protein synthesis in C2C12 myotubes.Autophagy induced by deficiency of sphingosine-1-phosphate phosphohydrolase 1 is switched to apoptosis by calpain-mediated autophagy-related gene 5 (Atg5) cleavage Bioactives of Artemisia dracunculus L. mitigate the role of ceramides in attenuating insulin signaling in rat skeletal muscle cells Sphingoid bases and the serine catabolic enzyme CHA1 define a novel feedforward/feedback mechanism in the response to serine availability Ceramide metabolism regulates autophagy and apoptotic cell death induced by melatonin in liver cancer cells.Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response.Autophagy is a protective mechanism for human melanoma cells under acidic stress.Sphingolipid-based drugs selectively kill cancer cells by down-regulating nutrient transporter proteins Ethylene Modulates Sphingolipid Synthesis in Arabidopsis.Glycosphingolipids and cell death: one aim, many ways Increased placental fatty acid transporter 6 and binding protein 3 expression and fetal liver lipid accumulation in a mouse model of obesity in pregnancy Sphingolipids: regulators of crosstalk between apoptosis and autophagy The role of lipids in the control of autophagy Nutrient transporters: the Achilles' heel of anabolism.Ablation of dihydroceramide desaturase 1, a therapeutic target for the treatment of metabolic diseases, simultaneously stimulates anabolic and catabolic signaling Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models.Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling.Loss of TSC2 confers resistance to ceramide and nutrient deprivation.Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways.Autophagy: regulation and role in disease.

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P2860

Ceramide starves cells to death by downregulating nutrient transporter proteins

http://www.wikidata.org/entity/Q36971061

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

@wuu

2008年论文

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2008年论文

@zh-cn

name

Ceramide starves cells to death by downregulating nutrient transporter proteins

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type

label

Ceramide starves cells to death by downregulating nutrient transporter proteins

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prefLabel

Ceramide starves cells to death by downregulating nutrient transporter proteins

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PNAS.0802781105

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Ceramide starves cells to death by downregulating nutrient transporter proteins

@en

P2093

Aimee L Edinger

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Eigen R Peralta

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Garret G Guenther

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Kimberly Romero Rosales

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Leah J Siskind

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Susan Y Wong

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P2860

Growth factors can influence cell growth and survival through effects on glucose metabolism

The AMP-activated protein kinase cascade--a unifying system for energy control

Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1

The roles of intracellular protein-degradation pathways in neurodegeneration

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

The role of autophagy during the early neonatal starvation period

Autophagy in cell death: an innocent convict?

Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer.

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