Generation of a 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-)_Ahrd mouse line harboring the poor-affinity aryl hydrocarbon receptor.
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Mechanisms of enzyme-catalyzed reduction of two carcinogenic nitro-aromatics, 3-nitrobenzanthrone and aristolochic acid I: Experimental and theoretical approachesContributions of the three CYP1 monooxygenases to pro-inflammatory and inflammation-resolution lipid mediator pathwaysBioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2.CYP1A1 and CYP1A2 expression: comparing 'humanized' mouse lines and wild-type mice; comparing human and mouse hepatoma-derived cell linesKnockout and humanized mice as suitable tools to identify enzymes metabolizing the human carcinogen aristolochic acid.Aryl hydrocarbon receptor (AHR): "pioneer member" of the basic-helix/loop/helix per-Arnt-sim (bHLH/PAS) family of "sensors" of foreign and endogenous signals.Identification of human cytochrome P450 enzymes involved in the metabolism of a novel к-opioid receptor agonist, nalfurafine hydrochloride.
P2860
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P2860
Generation of a 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-)_Ahrd mouse line harboring the poor-affinity aryl hydrocarbon receptor.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Generation of a 'humanized' hC ...... ity aryl hydrocarbon receptor.
@en
type
label
Generation of a 'humanized' hC ...... ity aryl hydrocarbon receptor.
@en
prefLabel
Generation of a 'humanized' hC ...... ity aryl hydrocarbon receptor.
@en
P2093
P2860
P1476
Generation of a 'humanized' hC ...... ity aryl hydrocarbon receptor.
@en
P2093
Daniel W Nebert
Hongbin Dong
Robyn M Amos-Kroohs
Zhanquan Shi
P2860
P304
P356
10.1016/J.BBRC.2008.09.068
P407
P577
2008-09-22T00:00:00Z