Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE
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Epidermal development in mammals: key regulators, signals from beneath, and stem cellsConditional gene expression in the mouse inner ear using Cre-loxP.Impaired integrin β3 delays endothelial cell regeneration and contributes to arteriovenous graft failure in mice.Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle developmentThe extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney developmentDll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cellsNotch lineages and activity in intestinal stem cells determined by a new set of knock-in miceThe canonical Notch signaling pathway: unfolding the activation mechanism.In vivo visualization of Notch1 proteolysis reveals the heterogeneity of Notch1 signaling activity in the mouse cochlea.Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice.Distinct Notch signaling outputs pattern the developing arterial system.Teneurin-1 is expressed in interconnected regions of the developing brain and is processed in vivoThe contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.Notch: architect, landscaper, and guardian of the intestine.Mammary development and breast cancer: the role of stem cellsNotch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development.Autophagy is involved in mouse kidney development and podocyte differentiation regulated by Notch signalling.Molecular genetic analysis of podocyte genes in focal segmental glomerulosclerosis--a review.Modulation of notch-1 signaling alleviates vascular endothelial growth factor-mediated diabetic nephropathy.Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate.Intestinal development and differentiation.Targeting Notch Signaling in Colorectal Cancer.Epidermal Notch signalling: differentiation, cancer and adhesion.Second-generation Notch1 activity-trap mouse line (N1IP::CreHI) provides a more comprehensive map of cells experiencing Notch1 activityAn overview of notch signaling in adult tissue renewal and maintenance.The story of Notch and chronic kidney disease.Expression of Notch pathway proteins correlates with albuminuria, glomerulosclerosis, and renal functionNonoverlapping functions for Notch1 and Notch3 during murine steady-state thymic lymphopoiesis.Atonal homolog 1 is required for growth and differentiation effects of notch/gamma-secretase inhibitors on normal and cancerous intestinal epithelial cells.Intestinal deletion of Pofut1 in the mouse inactivates notch signaling and causes enterocolitis.Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration.Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cellsTissue Specific Expression of Cre in Rat Tyrosine Hydroxylase and Dopamine Active Transporter-Positive Neurons.Real-time imaging of notch activation with a luciferase complementation-based reporter.Overview of genetic tools and techniques to study Notch signaling in mice.Chemokine 25-induced signaling suppresses colon cancer invasion and metastasis.Notch signal strength controls cell fate in the haemogenic endotheliumDifferent assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cellsMastermind-like transcriptional co-activator-mediated Notch signaling is indispensable for maintaining conjunctival epithelial identity.
P2860
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P2860
Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE
@en
type
label
Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE
@en
prefLabel
Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE
@en
P2093
P2860
P356
P1433
P1476
Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE
@en
P2093
Brandon Hadland
Hans Clevers
Jeroen Korving
Maaike van den Born
Marc Vooijs
Stacey Huppert
Thaddeus Stappenbeck
Zhenyi Liu
P2860
P304
P356
10.1242/DEV.02733
P407
P577
2007-02-01T00:00:00Z