Rescue of dystrophin expression in mdx mouse muscle by RNA/DNA oligonucleotides.
about
Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapyGene correction of the apolipoprotein (Apo) E2 phenotype to wild-type ApoE3 by in situ chimeraplasty.Genetic correction of splice site mutation in purified and enriched myoblasts isolated from mdx5cv mice.A comparison of synthetic oligodeoxynucleotides, DNA fragments and AAV-1 for targeted episomal and chromosomal gene repairGene and cell-mediated therapies for muscular dystrophy.Rad51p and Rad54p, but not Rad52p, elevate gene repair in Saccharomyces cerevisiae directed by modified single-stranded oligonucleotide vectors.Novel approaches to treat muscular dystrophies.The potential of nucleic acid repair in functional genomics.Manipulating the mammalian genome by homologous recombinationTherapeutic application of chimeric RNA/DNA oligonucleotide based gene therapy.The development and regulation of gene repair.Targeted gene repair -- in the arena.The myotubularin family of lipid phosphatases in disease and in spermatogenesisEngineered ribozymes as molecular tools for site-specific alteration of RNA sequence.Adeno-associated virus vector carrying human minidystrophin genes effectively ameliorates muscular dystrophy in mdx mouse model.Purloined mechanisms of bacterial immunity can cure muscular dystrophy.Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice.Therapeutics in duchenne muscular dystrophy.Targeted correction of single-base-pair mutations with adeno-associated virus vectors under nonselective conditions.Molecular-targeted therapy for Duchenne muscular dystrophy: progress and potential.Targeted approaches for gene therapy and the emergence of engineered meganucleases.Emerging gene editing strategies for Duchenne muscular dystrophy targeting stem cells.Targeted gene repair in mammalian cells using chimeric RNA/DNA oligonucleotides and modified single-stranded vectors.Enhanced gene repair mediated by methyl-CpG-modified single-stranded oligonucleotidesIn vivo gene repair of point and frameshift mutations directed by chimeric RNA/DNA oligonucleotides and modified single-stranded oligonucleotides.Strand bias in targeted gene repair is influenced by transcriptional activity.Homologous recombination is required for AAV-mediated gene targeting.Non-viral vector-mediated uptake, distribution, and stability of chimeraplasts in human airway epithelial cells.Functional correction of episomal mutations with short DNA fragments and RNA-DNA oligonucleotides.Single-stranded oligonucleotide-mediated in vivo gene repair in the rd1 retina.Use of chimeric DNA-RNA primers in quantitative PCR for detection of Ehrlichia canis and Babesia canis.Summary report of a symposium: genes and gene delivery for diseases of alcoholism.Targeted beta-globin gene conversion in human hematopoietic CD34(+ )and Lin(-)CD38(-)cells.Adeno-associated virus vector-mediated gene transfer into dystrophin-deficient skeletal muscles evokes enhanced immune response against the transgene product.Oligonucleotide-directed single-base DNA alterations in mouse embryonic stem cells.Targeting of A701G nucleotide at the human ATP1A1 locus using a RNA/DNA chimera.Long-term expression of full-length human dystrophin in transgenic mdx mice expressing internally deleted human dystrophins.Targeted gene correction by small single-stranded oligonucleotides in mammalian cells.Noninvasive monitoring of therapeutic gene transfer in animal models of muscular dystrophies.Ex vivo gene editing of the dystrophin gene in muscle stem cells mediated by peptide nucleic acid single stranded oligodeoxynucleotides induces stable expression of dystrophin in a mouse model for Duchenne muscular dystrophy.
P2860
Q28084979-22CBB14D-910F-4624-A4EC-9C681652080EQ30661436-F102B5EC-218A-44CF-9A28-547004E11A2FQ33411557-A03667B8-7774-4F46-BA19-663D95FFACB2Q33432320-1FF8115C-6DC8-44A6-B78C-B1E9E718A6A4Q33831193-33288748-756E-4B4B-8E7E-EDBF510F53FAQ33888510-72DB2534-373D-4D63-BAAA-74818F6ACBB9Q34204364-973AABCB-5F80-406C-BC24-53CAB2A0E8FDQ34205509-8AF1F161-1A6E-4EDE-8F4D-7F77DBBA488EQ34311686-CF6FE371-6101-404E-A059-80ED948C1DBDQ34452120-DD432194-9AB3-417B-914B-6AC5271638CAQ35209965-EC5701CB-FE0D-46D8-AFAA-096E346D29B8Q35210621-4FF061D9-5F26-4320-B322-96D860D0DED7Q35240346-05C81DB6-2765-45B8-9328-33B1A75F354DQ35549357-1327DDF7-00FE-42E6-8175-95A4AAAF0217Q35573761-CB69CEE9-9ADB-4A2F-8DBF-B6CABC837A1DQ35742769-1B481649-DEBD-4687-8F97-763579091B8BQ36324105-F0737643-C73C-4F30-AF6E-636B5FD8308DQ36428758-083A7DAE-35B3-4919-B3AD-23EFA38E0681Q37092798-F5F51EAB-6F0D-4642-AD9E-386E3B563F28Q37142004-43EF7DEB-2976-4F8C-A754-5D511BB29CF6Q37581606-90DF6572-9FB0-4F93-83B1-4A4FFA39A271Q38209315-CB82E895-A559-4A67-A810-1837F6783D78Q38293639-6CC7BF5A-32B4-4B28-A41B-0A85AD1DDD81Q38349381-A4618E38-EAC1-452A-92B7-AF1FA1A7524EQ39228801-D15B13E6-16D2-4396-8D0A-01CA4ABCC4F5Q39674772-D87346FD-28CC-4BC1-AE33-79F09C8CAD34Q40258601-3CA7D7BF-D185-4568-8093-AB151CC9C8CCQ40718952-A603C418-4CED-43A1-909A-ED039B5E766CQ40740212-473E511A-B4E6-4665-862F-AE5BFC9E1525Q41967044-80342A3C-7C9F-4558-BF21-D8A4E32C6D64Q42570372-DD12B556-89D4-4678-BC09-99B7E31B3F9AQ43848028-DA44DBD8-20BA-48C8-9C1E-FB2DDD474157Q45714297-2924DEAD-0AC8-4632-BDEF-1BFA9A2BB908Q45730194-CCDCE6E9-F01D-4140-91CD-8A1778589F3CQ45857714-0254A6CE-00BC-47A5-8D46-B2846F76ED54Q45857920-834DC3A0-7A2B-4FD3-8442-1C018CD4BA87Q45873225-1A990347-AAD7-4C0D-90F3-28B61BFBAAC6Q45876530-82085B81-09BB-4073-8DF7-39F261DB16B8Q45886068-DE3914D8-9591-47DF-BC3C-0DD862BDC713Q46449770-EBA0EB22-A016-4217-96BF-1BB3ABCD0843
P2860
Rescue of dystrophin expression in mdx mouse muscle by RNA/DNA oligonucleotides.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Rescue of dystrophin expression in mdx mouse muscle by RNA/DNA oligonucleotides.
@en
type
label
Rescue of dystrophin expression in mdx mouse muscle by RNA/DNA oligonucleotides.
@en
prefLabel
Rescue of dystrophin expression in mdx mouse muscle by RNA/DNA oligonucleotides.
@en
P2093
P2860
P356
P1476
Rescue of dystrophin expression in mdx mouse muscle by RNA/DNA oligonucleotides.
@en
P2093
P2860
P304
P356
10.1073/PNAS.97.10.5363
P407
P577
2000-05-01T00:00:00Z