Fluorinated Nucleosides: Synthesis and Biological Implication
about
Synthesis and antiviral evaluation of 2′,2′,3′,3′-tetrafluoro nucleoside analogsThiophene-expanded guanosine analogues of Gemcitabine.Investigation and conformational analysis of fluorinated nucleoside antibiotics targeting siderophore biosynthesis.Synthesis, evaluation of anti-HIV-1 and anti-HCV activity of novel 2',3'-dideoxy-2',2'-difluoro-4'-azanucleosidesGRL-04810 and GRL-05010, difluoride-containing nonpeptidic HIV-1 protease inhibitors (PIs) that inhibit the replication of multi-PI-resistant HIV-1 in vitro and possess favorable lipophilicity that may allow blood-brain barrier penetration.Raising the pKa limit of "soft" nucleophiles in palladium-catalyzed allylic substitutions: application of diarylmethane pronucleophiles.Medicinal applications of perfluoroalkylated chain-containing compounds.Aminophosphine Oxides: A Platform for Diversified Functions.Synthesis and biological activity of the nucleoside analogs based on polyfluoroalkyl-substituted 1,2,3-triazoles.New preparation and synthetic reactions of 3,3,3-trifluoropropynyllithium, -borate and -stannane: facile synthesis of trifluoromethylated allenes, arylacetylenes and enynes.Synthesis and antiviral evaluation of fluorinated acyclo-nucleosides and their phosphoramidates.High-performance liquid chromatography purification of chemically modified RNA aptamers.Combining asymmetric catalysis with natural product functionalization through enantioselective alpha-fluorination.A general and enantioselective approach to pentoses: a rapid synthesis of PSI-6130, the nucleoside core of sofosbuvir.Synthesis of 3'-fluoro-tRNA analogues for exploring non-ribosomal peptide synthesis in bacteria.From bifunctional to trifunctional (tricomponent nucleophile-transition metal-lewis acid) catalysis: the catalytic, enantioselective α-fluorination of acid chloridesSynthesis of trifluoromethyl-substituted pyrazolo[4,3-c]pyridines - sequential versus multicomponent reaction approach.Recombinant purine nucleoside phosphorylases from thermophiles: preparation, properties and activity towards purine and pyrimidine nucleosides.Base-catalyzed diastereoselective trimerization of trifluoroacetone.Fluorinated nucleosides as an important class of anticancer and antiviral agents.Intermolecular Palladium-Catalyzed Oxidative Fluorocarbonylation of Unactivated Alkenes: Efficient Access to β-Fluorocarboxylic Esters.Silver-catalyzed one-pot cyclization/fluorination of 2-alkynylanilines: highly efficient synthesis of structurally diverse fluorinated indole derivatives.Synthesis and biological applications of fluoro-modified nucleic acids.Synthesis, anti-HIV activity studies, and in silico rationalization of cyclobutane-fused nucleosides.HIV-Associated Neurocognitive Disorder (HAND) and the Prospect of Brain-Penetrating Protease Inhibitors for Antiretroviral Treatment.A facile synthesis of 5'-fluoro-5'-deoxyacadesine (5'-F-AICAR): a novel non-phosphorylable AICAR analogue.
P2860
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P2860
Fluorinated Nucleosides: Synthesis and Biological Implication
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Fluorinated Nucleosides: Synthesis and Biological Implication
@en
type
label
Fluorinated Nucleosides: Synthesis and Biological Implication
@en
prefLabel
Fluorinated Nucleosides: Synthesis and Biological Implication
@en
P2093
P2860
P1476
Fluorinated Nucleosides: Synthesis and Biological Implication
@en
P2093
Ashoke Sharon
Chung K Chu
P2860
P304
P356
10.1016/J.JFLUCHEM.2008.06.007
P577
2008-09-01T00:00:00Z