A prototypical Sigma-1 receptor antagonist protects against brain ischemia.
about
In vitro evaluation of guanidine analogs as sigma receptor ligands for potential anti-stroke therapeuticsRole of sigma receptors in methamphetamine-induced neurotoxicityAC927, a σ receptor ligand, blocks methamphetamine-induced release of dopamine and generation of reactive oxygen species in NG108-15 cellsActivation of the Sigma-1 receptor by haloperidol metabolites facilitates brain-derived neurotrophic factor secretion from human astrogliaSigma-1 receptors regulate Bcl-2 expression by reactive oxygen species-dependent transcriptional regulation of nuclear factor kappaBNeuroprotective effects of high affinity Σ1 receptor selective compounds.Sigma-1 receptors and animal studies centered on pain and analgesia.Expression of a truncated form of the endoplasmic reticulum chaperone protein, σ1 receptor, promotes mitochondrial energy depletion and apoptosis.The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington diseaseCM156, a high affinity sigma ligand, attenuates the stimulant and neurotoxic effects of methamphetamine in miceFeasibility, efficacy, and safety of antipsychotics for intensive care unit delirium: the MIND randomized, placebo-controlled trial.Sigma receptors [σRs]: biology in normal and diseased statesAttenuation of methamphetamine-induced effects through the antagonism of sigma (sigma) receptors: Evidence from in vivo and in vitro studiesA possibly sigma-1 receptor mediated role of dimethyltryptamine in tissue protection, regeneration, and immunity.Role of peripheral sigma-1 receptors in ischaemic pain: Potential interactions with ASIC and P2X receptors.The Sigma-1 Receptor Antagonist, S1RA, Reduces Stroke Damage, Ameliorates Post-Stroke Neurological Deficits and Suppresses the Overexpression of MMP-9.Sigma-1 Receptors and Neurodegenerative Diseases: Towards a Hypothesis of Sigma-1 Receptors as Amplifiers of Neurodegeneration and Neuroprotection.Sigma-1 receptor agonist PRE084 is protective against mutant huntingtin-induced cell degeneration: involvement of calpastatin and the NF-κB pathway.2-Aminopyridine derivatives as potential σ(2) receptor antagonists.The 14th International Conference on Alzheimer's Drug Discovery, 9 - 10 September 2013, in Jersey City, New Jersey.Sigma-1 Receptor and Pain.
P2860
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P2860
A prototypical Sigma-1 receptor antagonist protects against brain ischemia.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A prototypical Sigma-1 receptor antagonist protects against brain ischemia.
@en
type
label
A prototypical Sigma-1 receptor antagonist protects against brain ischemia.
@en
prefLabel
A prototypical Sigma-1 receptor antagonist protects against brain ischemia.
@en
P2093
P2860
P1433
P1476
A prototypical Sigma-1 receptor antagonist protects against brain ischemia.
@en
P2093
Evelyn Perez
James W Simpkins
John A Schetz
Shiuhwei Chen
P2860
P356
10.1016/J.BRAINRES.2007.08.068
P407
P577
2007-09-12T00:00:00Z