Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.

Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.

Item
http://www.wikidata.org/entity/Q36977690
Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model.Neuronal activity modifies the chromatin accessibility landscape in the adult brain.Genetic driver mutations define the expression signature and microenvironmental composition of high-grade gliomas.Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma.Intrinsic Astrocyte Heterogeneity Influences Tumor Growth in Glioma Mouse Models.Genomic profiles of low-grade murine gliomas evolve during progression to glioblastoma.Revisit the Candidacy of Brain Cell Types as the Cell(s) of Origin for Human High-Grade Glioma.MerTK as a therapeutic target in glioblastoma.PIK3CA missense mutations promote glioblastoma pathogenesis, but do not enhance targeted PI3K inhibition
P2860

Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.

Item
http://www.wikidata.org/entity/Q36977690
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Core pathway mutations induce ...... but resistant to temozolomide.
@en
type
label
Core pathway mutations induce ...... but resistant to temozolomide.
@en
prefLabel
Core pathway mutations induce ...... but resistant to temozolomide.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Core pathway mutations induce ...... but resistant to temozolomide
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932