Design of aging intervention studies: the NIA interventions testing program.
about
The TOR pathway comes of ageEvaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous miceRapamycin fed late in life extends lifespan in genetically heterogeneous miceBuilding for the future: essential infrastructure for rodent ageing studiesGeroscience approaches to increase healthspan and slow agingBiochemical Genetic Pathways that Modulate Aging in Multiple SpeciesPathobiology of aging mice and GEM: background strains and experimental designRapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restrictionMitochondrial dysfunction in cardiac agingAging biology and novel targets for drug discovery.Late-life rapamycin treatment reverses age-related heart dysfunction.Long-term α1B-adrenergic receptor activation shortens lifespan, while α1A-adrenergic receptor stimulation prolongs lifespan in association with decreased cancer incidence.Meta-profiles of gene expression during aging: limited similarities between mouse and human and an unexpectedly decreased inflammatory signature.Aging biology: a new frontier for drug discovery.Calorie restriction: what recent results suggest for the future of ageing researchMice as a mammalian model for research on the genetics of agingMetabolism, genomics, and DNA repair in the mouse aging liver.RasGrf1 deficiency delays aging in mice.Autophagy and cartilage homeostasis mechanisms in joint health, aging and OARapamycin and ageing: when, for how long, and how much?Metallothionein and the biology of aging.Practical pathology of aging mice.Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan.Diet and aging.Why genes extending lifespan in model organisms have not been consistently associated with human longevity and what it means to translation researchSorbitol treatment extends lifespan and induces the osmotic stress response in Caenorhabditis elegans.Early and delayed intervention with rapamycin prevents NNK-induced lung adenocarcinoma in A/J mice.Longevity and aging.Rapamycin extends life span of Rb1+/- mice by inhibiting neuroendocrine tumorsHot topics in aging research: protein translation, 2009.Pathology is a critical aspect of preclinical aging studiesExploring the role of genetic variability and lifestyle in oxidative stress response for healthy aging and longevity.The Geropathology Research Network: An Interdisciplinary Approach for Integrating Pathology Into Research on Aging.Depressed pacemaker activity of sinoatrial node myocytes contributes to the age-dependent decline in maximum heart rate.Barriers to the Preclinical Development of Therapeutics that Target Aging Mechanisms.mTOR Inhibition: From Aging to Autism and Beyond.Of mice and CRISPR: The post-CRISPR future of the mouse as a model system for the human condition.Aging and cancer: can mTOR inhibitors kill two birds with one drug?Natural compounds with anti-ageing activity.Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity.
P2860
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P2860
Design of aging intervention studies: the NIA interventions testing program.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Design of aging intervention studies: the NIA interventions testing program.
@en
type
label
Design of aging intervention studies: the NIA interventions testing program.
@en
prefLabel
Design of aging intervention studies: the NIA interventions testing program.
@en
P2093
P2860
P1433
P1476
Design of aging intervention studies: the NIA interventions testing program.
@en
P2093
D E Harrison
J M Peralba
R A Miller
P2860
P304
P356
10.1007/S11357-008-9048-1
P577
2008-04-18T00:00:00Z