Egr2 is required for Bcl-2 induction during positive selection.
about
The essential function for serum response factor in T-cell development reflects its specific coupling to extracellular signal-regulated kinase signalingThe transcription factor c-Myb primes CD4+CD8+ immature thymocytes for selection into the iNKT lineage.Early growth response gene-2 (Egr-2) regulates the development of B and T cells.The Ras/MAPK pathway is required for generation of iNKT cells.Histone deacetylase 3 is required for iNKT cell developmentTenuous paths in unexplored territory: From T cell receptor signaling to effector gene expression during thymocyte selection.EGR2 is critical for peripheral naïve T-cell differentiation and the T-cell response to influenza.Zfat-deficiency results in a loss of CD3ζ phosphorylation with dysregulation of ERK and Egr activities leading to impaired positive selection.A role for p120 RasGAP in thymocyte positive selection and survival of naive T cells.Genetic association of the EGR2 gene with bipolar disorder in KoreaThe Ras GTPase-activating protein neurofibromin 1 promotes the positive selection of thymocytes.Egr2 and Egr3 in regulatory T cells cooperatively control systemic autoimmunity through Ltbp3-mediated TGF-β3 production.Control of early stages in invariant natural killer T-cell development.Triggering receptor expressed on myeloid cells 1 (TREM-1)-mediated Bcl-2 induction prolongs macrophage survival.The corepressor NCOR1 regulates the survival of single-positive thymocytes.Nab2 maintains thymus cellularity with aging and stress.Gli3 in fetal thymic epithelial cells promotes thymocyte positive selection and differentiation by repression of Shh.Egr2 induced during DC development acts as an intrinsic negative regulator of DC immunogenicity.Developing NKT cells need their calcium.ERK Signaling Controls Innate-like CD8 T Cell Differentiation via the ELK4 (SAP-1) and ELK1 Transcription Factors
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P2860
Egr2 is required for Bcl-2 induction during positive selection.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Egr2 is required for Bcl-2 induction during positive selection.
@en
type
label
Egr2 is required for Bcl-2 induction during positive selection.
@en
prefLabel
Egr2 is required for Bcl-2 induction during positive selection.
@en
P2093
P2860
P1476
Egr2 is required for Bcl-2 induction during positive selection.
@en
P2093
David L Wiest
Jens-Peter Holst Lauritsen
José Alberola-Ila
Juliette M Lefebvre
Michele Rhodes
Sang-Yun Lee
Sridevi Kurella
P2860
P304
P356
10.4049/JIMMUNOL.181.11.7778
P407
P577
2008-12-01T00:00:00Z