Caspofungin modulates inflammatory responses to Aspergillus fumigatus through stage-specific effects on fungal beta-glucan exposure.
about
Characterization of a distinct host response profile to Pneumocystis murina asci during clearance of pneumocystis pneumoniaEchinocandin treatment of pneumocystis pneumonia in rodent models depletes cysts leaving trophic burdens that cannot transmit the infectionDynamic, morphotype-specific Candida albicans beta-glucan exposure during infection and drug treatmentIn vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosisInnate immunity to Aspergillus species.Modulation of Alternaria infectoria cell wall chitin and glucan synthesis by cell wall synthase inhibitors.Endoplasmic reticulum localized PerA is required for cell wall integrity, azole drug resistance, and virulence in Aspergillus fumigatus.Breakthrough invasive candidiasis in patients on micafungin.Treatment options in Invasive Aspergillosis.Dectin-1: a role in antifungal defense and consequences of genetic polymorphisms in humans.Evidence supporting a role for mammalian chitinases in efficacy of caspofungin against experimental aspergillosis in immunocompromised ratsMicafungin in the treatment of invasive candidiasis and invasive aspergillosisCandida albicans infections in renal transplant recipients: effect of caspofungin on polymorphonuclear cellsDifferences in efficacy and cytokine profiles following echinocandin or liposomal amphotericin B monotherapy or combination therapy for murine pulmonary or systemic Aspergillus flavus infectionsAspergillus terreus accessory conidia are multinucleated, hyperpolarizing structures that display differential dectin staining and can induce heightened inflammatory responses in a pulmonary model of aspergillosis.Innate inflammatory response and immunopharmacologic activity of micafungin, caspofungin, and voriconazole against wild-type and FKS mutant Candida glabrata isolates.Role of innate immune receptors in paradoxical caspofungin activity in vivo in preclinical aspergillosis.Echinocandin Resistance in Candida.Albumin Enhances Caspofungin Activity against Aspergillus Species by Facilitating Drug Delivery to Germinating Hyphae.Cell Wall Changes in Amphotericin B-Resistant Strains from Candida tropicalis and Relationship with the Immune Responses Elicited by the HostRedundant catalases detoxify phagocyte reactive oxygen and facilitate Histoplasma capsulatum pathogenesisHypoxia enhances innate immune activation to Aspergillus fumigatus through cell wall modulation.CD5 sweetens lymphocyte responsesFungal cell wall dynamics and infection site microenvironments: signal integration and infection outcome.Defining responses to therapy and study outcomes in clinical trials of invasive fungal diseases: Mycoses Study Group and European Organization for Research and Treatment of Cancer consensus criteria.Stage-specific innate immune recognition of Aspergillus fumigatus and modulation by echinocandin drugs.Deletion of the α-(1,3)-glucan synthase genes induces a restructuring of the conidial cell wall responsible for the avirulence of Aspergillus fumigatus.Pattern recognition: recent insights from Dectin-1Current perspectives on echinocandin class drugs.Invasive fungal infections in the ICU.Antifungal prophylaxis and therapy in patients with hematological malignancies and hematopoietic stem cell transplant recipients.Immune responses against Aspergillus fumigatus: what have we learned?Immunomodulatory properties of antifungal agents on phagocytic cells.Pathogenesis and host defence against Mucorales: the role of cytokines and interaction with antifungal drugs.Macrophage reporter cell assay for screening immunopharmacological activity of cell wall-active antifungals.Caspofungin: Pharmacodynamics, pharmacokinetics, clinical uses and treatment outcomes.Echinocandins: The Expanding Antifungal Armamentarium.Caspofungin-Mediated Growth Inhibition and Paradoxical Growth in Aspergillus fumigatus involve Fungicidal Hyphal Tip Lysis Coupled with Regenerative Intrahyphal Growth and Dynamic Changes in β-1,3-Glucan Synthase Localization.Fungal echinocandin resistance.Surfactant protein D binding to Aspergillus fumigatus hyphae is calcineurin-sensitive.
P2860
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P2860
Caspofungin modulates inflammatory responses to Aspergillus fumigatus through stage-specific effects on fungal beta-glucan exposure.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Caspofungin modulates inflamma ...... n fungal beta-glucan exposure.
@en
type
label
Caspofungin modulates inflamma ...... n fungal beta-glucan exposure.
@en
prefLabel
Caspofungin modulates inflamma ...... n fungal beta-glucan exposure.
@en
P2093
P2860
P356
P1476
Caspofungin modulates inflamma ...... on fungal beta-glucan exposure
@en
P2093
D S Perlin
M Feldmesser
P2860
P304
P356
10.1086/589304
P407
P577
2008-07-01T00:00:00Z