Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy. - Wikidata - awgldk - TriplyDB

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy.

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy.

http://www.wikidata.org/entity/Q36988176

about

Glucose represses dendritic cell-induced T cell responses.Global Analysis of O-GlcNAc Glycoproteins in Activated Human T Cells Lighting Up T Lymphocyte Signaling with Quantitative Phosphoproteomics.CCCTC-Binding Factor Translates Interleukin 2- and α-Ketoglutarate-Sensitive Metabolic Changes in T Cells into Context-Dependent Gene Programs.Control of amino acid transport coordinates metabolic reprogramming in T-cell malignancy.O-GlcNAcylation in Cancer Biology: Linking Metabolism and Signaling.Metabolic Hallmarks of Tumor and Immune Cells in the Tumor Microenvironment Immunometabolism in early and late stages of rheumatoid arthritis.O-GlcNAcylation and chromatin remodeling in mammals: an up-to-date overview.EOGT and O-GlcNAc on secreted and membrane proteins.Reenergizing T cell anti-tumor immunity by harnessing immunometabolic checkpoints and machineries.Metabolic Instruction of Immunity.Mitochondrial Control and Guidance of Cellular Activities of T Cells.Protein O-GlcNAcylation: emerging mechanisms and functions.The emerging link between O-GlcNAcylation and neurological disorders.Ancillary Activity: Beyond Core Metabolism in Immune Cells.Similarities and Distinctions of Cancer and Immune Metabolism in Inflammation and Tumors.Metabolic orchestration of T lineage differentiation and function.Glutaminase expression is a poor prognostic factor in node-positive triple-negative breast cancer patients with a high level of tumor-infiltrating lymphocytes.Myeloid-derived cullin 3 promotes STAT3 phosphorylation by inhibiting OGT expression and protects against intestinal inflammation.Glucose- and glutamine-fueled stabilization of C-Myc is required for T-cell proliferation and malignant transformation Protein glycosylation energizes T cells.Profiling of Protein O-GlcNAcylation in Murine CD8+ Effector- and Memory-like T Cells.O-GlcNAcylation is required for B cell homeostasis and antibody responses.Sugar or Fat?-Metabolic Requirements for Immunity to Viral Infections.c-MYC mRNA tail tale about glutamine control of transcription.Mapping and quantification of over 2,000 O-linked glycopeptides in activated human T cells with isotope-targeted glycoproteomics (IsoTaG).MicroRNA-15b Suppresses Th17 Differentiation and Is Associated with Pathogenesis of Multiple Sclerosis by Targeting O-GlcNAc Transferase.Change of the metabolomic profile during short-term mononuclear cell storage.Oncogenic KRAS and the EGFR loop in pancreatic carcinogenesis-A connection to licensing nodes.Effects of hypo O-GlcNAcylation on Drosophila development.Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice.The Nutrient-Sensing Hexosamine Biosynthetic Pathway as the Hub of Cancer Metabolic Rewiring.Hexosamine Biosynthetic Pathway Inhibition Leads to AML Cell Differentiation and Cell Death mTOR Regulation of Glycolytic Metabolism in T Cells Hematopoietic stem cell specific V-ATPase controls breast cancer progression and metastasis via cytotoxic T cells Targeting T Cell Metabolism for Improvement of Cancer Immunotherapy The Influence of Metabolism on Drug Response in Cancer

P2860

Q33766590-147032C7-C150-4275-8704-A6B0F1B0CC00 Q37321175-63472A4B-7FFB-42C4-B265-139E230F1581 Q38604840-DC6DF3DB-CD48-4F23-9A73-225CA3ECF662 Q38622052-193548FE-FE9B-4EF6-9ED0-B918793C238A Q38762740-B6CB25F1-77FA-44B6-AAAD-6E2BCB6B563E Q38876699-72CD130A-FECA-48BC-8486-8DA19E66C452 Q39197674-E7EBDE6D-6D68-45CC-9870-7440B58BF607 Q39209693-31EA0B9C-3EDE-4889-8AA9-8F8D4AAC48F3 Q39241437-48B8A5ED-0069-4139-951E-D7171A09C836 Q39241488-FD128673-1F24-4656-BF7C-C754043B1E40 Q39273837-A68ECB37-30F6-48F4-A438-4C75E5BC4442 Q39286043-02A1A0A8-8282-449D-BBF0-64126B1BEF96 Q39292530-5C3099EE-CBCB-4972-8884-80E317DDC989 Q39295247-E89A9BA4-91B0-4DD4-A08D-D67CD2E0BB8A Q39324009-1306BBAD-FA4D-4759-803A-ABFDDB35A8C9 Q39418519-B23FC4D3-4D0E-4FA4-B972-26B8F9AE72DB Q39418532-E877C58F-9382-4890-A790-5FA82B64686C Q40049632-053D2007-D71D-4E71-AB26-C8340322101B Q40341736-24499391-5286-4415-A2F0-1F54F9EAA0CD Q41978406-FE7331BA-FA7F-4624-8902-E15082B73F8A Q42367894-7CB94C5D-BDD5-4D84-AC35-D5E634ACB12F Q46010782-EC1A9B69-D9B7-4477-95B1-4243BFDFD445 Q46076973-880F9B96-50D9-4481-B369-6D1687F70A20 Q47113112-AD91B1EA-139A-41C2-85B9-493B608F559B Q47160410-7090E345-9D3B-40D9-B2FE-22075F861AAB Q48141895-9740E908-EC46-42A8-9BB8-511CFF92ED37 Q49913262-FC01817A-6D62-4CFD-9DFF-23FAE976DAC8 Q50878107-B8B824B4-A474-46CA-A95F-66307788428A Q50973215-979FC8D9-9E92-4DC3-8264-32C1618262FF Q51049205-EE2C896C-43CB-4B6C-AA5B-C96BBC9A150C Q52339982-4E750039-0D1C-44C0-BB98-88E76A1B192E Q55252861-D42417A1-2EC7-4877-B960-BF766E076E5A Q55497180-554D7940-BA89-4DFD-8A3B-B4AE467EA259 Q57143658-E106AFF2-3035-48BA-B140-ACDC7FFB850B Q57491938-98FA31CA-F010-4A61-83B3-96BFC4C52AB1 Q58764400-543625D2-23C5-4A39-8422-B2A0562C2E91 Q58801754-88E88A1D-5DFC-4A34-93A1-E48F1C8113A6 Q59136910-796E6721-A3C7-4525-9920-665E1C0D4DD5

P2860

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy.

http://www.wikidata.org/entity/Q36988176

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Glucose and glutamine fuel pro ...... l self-renewal and malignancy.

@en

type

label

Glucose and glutamine fuel pro ...... l self-renewal and malignancy.

@en

prefLabel

Glucose and glutamine fuel pro ...... l self-renewal and malignancy.

@en

P1433

Q36988176-462E88EF-9BB5-4190-9068-7B731FDDCD91

P1476

Q36988176-9CEAD06E-09FF-4E22-9557-E9DF553FC213

P2093

Q36988176-5D049AF3-EA96-44F7-A2BB-F5FCA6E39BB5

Q36988176-6DB61D2C-88F1-40ED-AB71-1DA01297811B

Q36988176-8BF59505-7995-4B44-91F5-F3B36059AAA4

Q36988176-AD68E2A1-C66B-43D2-9356-32656B56E7FD

Q36988176-ED1738A2-DF30-4B51-9907-19AF2AC30301

P2860

Q36988176-04C33FBE-01C9-471A-B15C-52AEC0450C79

Q36988176-0B77FEDB-CE1B-49BC-A59B-530980F2DA77

Q36988176-1078B2F0-48F4-43E0-A3DF-C4CC8A55C671

Q36988176-11634D21-4955-44FF-9A59-BE67321C389E

Q36988176-155470C5-159A-44A2-945E-F3F5C5C32528

Q36988176-159BA167-425F-458A-8266-E6ACF3F5EC9A

Q36988176-1998CCC5-5307-48F6-8AEC-B218B94F8A24

Q36988176-26157E14-9B4F-414C-95D4-AA9055A10BC0

Q36988176-303A2B8E-E03E-43FB-B71C-264B32CAD2F5

Q36988176-333BD44D-CDBC-426F-8926-E0D47C435FBA

P2888

Q36988176-9155E3C3-6B60-4D99-9C0D-28DC683FB485

P304

Q36988176-56935BDF-121E-4883-A84D-8425FDA7AA29

P31

Q36988176-3272810F-9613-4EA0-A51B-9C06535F81F0

P356

Q36988176-F208E228-5643-4988-93E9-A244E7AE795E

P407

Q36988176-10E7850D-F1EC-46E2-87FB-583D2AB133B2

P433

Q36988176-72610C3B-07FF-4BB4-8278-86A1D41F8183

P478

Q36988176-82FFCCAF-6FF9-4514-A99D-F33C7E37E99C

P50

Q36988176-37EB2BA4-9FDC-4B83-AC6F-0F8B33A5EBC1

Q36988176-77ED8D66-73EB-43A2-A638-388C2B1C2D8F

P577

Q36988176-CF692A38-41D8-46B2-A497-EDDAAE86A252

P6179

Q36988176-B771D565-C705-428B-A034-F439D289A130

P698

Q36988176-7F5F9F34-A1A3-4892-802A-40207C1BB077

P932

Q36988176-2868C80D-9198-46C2-8AB8-98BF52507B3E

P356

P1433

Nature Immunology

P1476

Glucose and glutamine fuel pro ...... l self-renewal and malignancy.

@en

P2093

Doreen A Cantrell

http://www.w3.org/2001/XMLSchema#string

Katarzyna M Grzes

http://www.w3.org/2001/XMLSchema#string

Linda V Sinclair

http://www.w3.org/2001/XMLSchema#string

Sebastian Damerow

http://www.w3.org/2001/XMLSchema#string

Shalini Pathak

http://www.w3.org/2001/XMLSchema#string

P2860

Induction of glucose metabolism in stimulated T lymphocytes is regulated by mitogen-activated protein kinase signaling

Requirement for O-linked N-acetylglucosaminyltransferase in lymphocytes activation

The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny

Cell-Penetrant, Nanomolar O-GlcNAcase Inhibitors Selective against Lysosomal Hexosaminidases

c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas

Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins

Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis

Activation of the transcriptional function of the NF-κB protein c-Rel by O-GlcNAc glycosylation

Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation.

The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function

P2888

P304

712-720

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NI.3439

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

17

http://www.w3.org/2001/XMLSchema#string

P50

Daan van Aalten

P577

2016-04-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P6179

1033209585

http://www.w3.org/2001/XMLSchema#string

P698

27111141

http://www.w3.org/2001/XMLSchema#string

P932

4900450

http://www.w3.org/2001/XMLSchema#string