Molecular mechanisms of multiple toxin-antitoxin systems are coordinated to govern the persister phenotype
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Toxin-Antitoxin Modules Are Pliable Switches Activated by Multiple Protease PathwaysEmerging Roles of Toxin-Antitoxin Modules in Bacterial PathogenesisSub-Optimal Treatment of Bacterial BiofilmsToxin-Antitoxin systems: their role in persistence, biofilm formation, and pathogenicityThe Antitoxin Protein of a Toxin-Antitoxin System from Xylella fastidiosa Is Secreted via Outer Membrane VesiclesHeterogeneous persister cells formation in Acinetobacter baumanniiAnalysis of non-typeable Haemophilous influenzae VapC1 mutations reveals structural features required for toxicity and flexibility in the active siteTackling Drug Resistant Infection Outbreaks of Global Pandemic Escherichia coli ST131 Using Evolutionary and Epidemiological Genomics.Biofilm-related infections: bridging the gap between clinical management and fundamental aspects of recalcitrance toward antibiotics.Noise Reduction in Complex Biological Switches.HipA-mediated antibiotic persistence via phosphorylation of the glutamyl-tRNA-synthetase.Sublethal concentrations of carbapenems alter cell morphology and genomic expression of Klebsiella pneumoniae biofilmsNutrient transitions are a source of persisters in Escherichia coli biofilmsToxin-antitoxin systems in the mobile genome of Acidithiobacillus ferrooxidans.One cannot rule them all: Are bacterial toxins-antitoxins druggable?Transcriptional Adaptation of Drug-tolerant Mycobacterium tuberculosis During Treatment of Human TuberculosisDesign Space Toolbox V2: Automated Software Enabling a Novel Phenotype-Centric Modeling Strategy for Natural and Synthetic Biological Systems.Human Granulocyte Macrophage Colony-Stimulating Factor Enhances Antibiotic Susceptibility of Pseudomonas aeruginosa Persister Cells.Regulatory crosstalk between type I and type II toxin-antitoxin systems in the human pathogen Enterococcus faecalis.Antibiotic-tolerant Staphylococcus aureus Biofilm Persists on Arthroplasty Materials.Phenotypic deconstruction of gene circuitryAntibiotic resistance: a physicist's view.Growth feedback as a basis for persister bistability.Bacterial growth: global effects on gene expression, growth feedback and proteome partition.What makes the lac-pathway switch: identifying the fluctuations that trigger phenotype switching in gene regulatory systems.Effects of meropenem exposure in persister cells of Acinetobacter calcoaceticus-baumannii.Elucidating the genotype-phenotype map by automatic enumeration and analysis of the phenotypic repertoire.Structural conservation of the PIN domain active site across all domains of life.Rapid Discrimination Among Putative Mechanistic Models of Biochemical SystemsDiversity, Prevalence, and Longitudinal Occurrence of Type II Toxin-Antitoxin Systems of Pseudomonas aeruginosa Infecting Cystic Fibrosis Lungs.The innate growth bistability and fitness landscapes of antibiotic-resistant bacteria.The vapB-vapC Operon of Acidovorax citrulli Functions as a Bona-fide Toxin-Antitoxin ModuleUnrelated toxin-antitoxin systems cooperate to induce persistence.Persistence and resistance as complementary bacterial adaptations to antibiotics.A Nonsynonymous SNP Catalog of Mycobacterium tuberculosis Virulence Genes and Its Use for Detecting New Potentially Virulent SublineagesPhysical and Functional Interplay between MazF1Bif and Its Noncognate Antitoxins from Bifidobacterium longumFic Proteins of Campylobacter fetus subsp. venerealis Form a Network of Functional Toxin-Antitoxin Systems.Strategy revealing phenotypic differences among synthetic oscillator designs.Relating switching rates between normal and persister cells to substrate and antibiotic concentrations: a mathematical modelling approach supported by experiments.Synchronized switching of multiple toxin-antitoxin modules by (p)ppGpp fluctuation.
P2860
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P2860
Molecular mechanisms of multiple toxin-antitoxin systems are coordinated to govern the persister phenotype
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Molecular mechanisms of multip ...... govern the persister phenotype
@en
type
label
Molecular mechanisms of multip ...... govern the persister phenotype
@en
prefLabel
Molecular mechanisms of multip ...... govern the persister phenotype
@en
P2860
P356
P1476
Molecular mechanisms of multip ...... govern the persister phenotype
@en
P2093
Michael A Savageau
Rick A Fasani
P2860
P304
P356
10.1073/PNAS.1301023110
P407
P577
2013-06-18T00:00:00Z