Hyper IgM immunodeficiency. A primary dysfunction of B lymphocyte isotype switching
about
Cyclosporin A inhibits CD40 ligand expression in T lymphocytes.Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgMSignaling through CD40 rescues IgE but not IgG or IgA secretion in X-linked immunodeficiency with hyper-IgM.Intrinsic defect in B cells of patients with hyper-immunoglobulin M syndrome.Memory B cell development but not germinal center formation is impaired by in vivo blockade of CD40-CD40 ligand interaction.Disodium cromoglycate inhibits S mu-->S epsilon deletional switch recombination and IgE synthesis in human B cells.Immunoglobulin class switch recombination deficiency type 1 or CD40 ligand deficiency: from bedside to bench and back again.Long-term outcomes of 176 patients with X-linked hyper-IgM syndrome treated with or without hematopoietic cell transplantation.Definition of the gene loci in X-linked immunodeficiencies.Presence of immunoglobulin (Ig) M and IgG double isotype-bearing cells and defect of switch recombination in hyper IgM immunodeficiency.Human malignant T cells capable of inducing an immunoglobulin class switch.
P2860
Q30449273-9B56AE10-1D37-4937-936E-B2E9CBFFD138Q30454072-C7432EA6-E76B-4614-93B2-BB94495B0720Q34199490-CA7EB1F4-1142-4E54-8B3C-6A16A57BCE10Q35224646-C74E5ADE-4A4C-4123-9E9A-2CDBF9595151Q36363287-9B74BF96-4F3F-4C9B-9871-F8DCAC5B7EA1Q36363488-26D3BB35-DABC-4E23-A7B7-390175A54854Q38168950-1BFEA794-5D8A-4A91-AA3B-E5E5AD57F83CQ39327528-ADF27A71-AD53-436B-8B2A-BD949D49BF08Q39545257-8FCA57B3-19CA-48FA-AA74-1655BA60BB8EQ40347275-12BE18CB-1F8A-4750-9DAF-CCCFA390DB6CQ41889398-8F997DDA-6712-4F7D-9972-91387B455F3E
P2860
Hyper IgM immunodeficiency. A primary dysfunction of B lymphocyte isotype switching
description
1983 nî lūn-bûn
@nan
1983年の論文
@ja
1983年論文
@yue
1983年論文
@zh-hant
1983年論文
@zh-hk
1983年論文
@zh-mo
1983年論文
@zh-tw
1983年论文
@wuu
1983年论文
@zh
1983年论文
@zh-cn
name
Hyper IgM immunodeficiency. A primary dysfunction of B lymphocyte isotype switching
@en
type
label
Hyper IgM immunodeficiency. A primary dysfunction of B lymphocyte isotype switching
@en
prefLabel
Hyper IgM immunodeficiency. A primary dysfunction of B lymphocyte isotype switching
@en
P2093
P2860
P356
P1476
Hyper IgM immunodeficiency. A primary dysfunction of B lymphocyte isotype switching
@en
P2093
P2860
P304
P356
10.1172/JCI111124
P407
P577
1983-11-01T00:00:00Z