Gain-of-function mutations in the transcription factor MRR1 are responsible for overexpression of the MDR1 efflux pump in fluconazole-resistant Candida dubliniensis strains.
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The transcription factor Ndt80 does not contribute to Mrr1-, Tac1-, and Upc2-mediated fluconazole resistance in Candida albicansGenetic Basis of Antifungal Drug ResistanceModeling the transcriptional regulatory network that controls the early hypoxic response in Candida albicansOropharyngeal candidiasis in the era of antiretroviral therapySAGA/ADA complex subunit Ada2 is required for Cap1- but not Mrr1-mediated upregulation of the Candida albicans multidrug efflux pump MDR1Regulation of efflux pump expression and drug resistance by the transcription factors Mrr1, Upc2, and Cap1 in Candida albicans.Functional dissection of a Candida albicans zinc cluster transcription factor, the multidrug resistance regulator Mrr1.Development of fluconazole resistance in a series of Candida parapsilosis isolates from a persistent candidemia patient with prolonged antifungal therapyFluconazole and Voriconazole Resistance in Candida parapsilosis Is Conferred by Gain-of-Function Mutations in MRR1 Transcription Factor Gene.Molecular mechanisms of drug resistance in clinical Candida species isolated from Tunisian hospitalsThe synthesis, regulation, and functions of sterols in Candida albicans: Well-known but still lots to learn.An MDR1 promoter allele with higher promoter activity is common in clinically isolated strains of Candida albicansMechanisms of antifungal drug resistance in Candida dubliniensis.Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus.The development of fluconazole resistance in Candida albicans - an example of microevolution of a fungal pathogen.Antifungal resistance and new strategies to control fungal infections.Competitive Fitness of Fluconazole-Resistant Clinical Candida albicans Strains.Molecular mechanisms of fluconazole resistance in Candida parapsilosis isolates from a U.S. surveillance system.Transcriptional profiling of azole-resistant Candida parapsilosis strainsInducible and constitutive activation of two polymorphic promoter alleles of the Candida albicans multidrug efflux pump MDR1.An acquired mechanism of antifungal drug resistance simultaneously enables Candida albicans to escape from intrinsic host defenses.Induction of Candida albicans drug resistance genes by hybrid zinc cluster transcription factors.Analysis of a fungus-specific transcription factor family, the Candida albicans zinc cluster proteins, by artificial activation.Cdr2p contributes to fluconazole resistance in Candida dubliniensis clinical isolates
P2860
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P2860
Gain-of-function mutations in the transcription factor MRR1 are responsible for overexpression of the MDR1 efflux pump in fluconazole-resistant Candida dubliniensis strains.
description
2008 nî lūn-bûn
@nan
2008年の論文
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2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Gain-of-function mutations in ...... Candida dubliniensis strains.
@en
type
label
Gain-of-function mutations in ...... Candida dubliniensis strains.
@en
prefLabel
Gain-of-function mutations in ...... Candida dubliniensis strains.
@en
P2093
P2860
P356
P1476
Gain-of-function mutations in ...... Candida dubliniensis strains.
@en
P2093
Joachim Morschhäuser
P David Rogers
Sabrina Schubert
P2860
P304
P356
10.1128/AAC.00740-08
P407
P577
2008-09-22T00:00:00Z