Controlled human infection and rechallenge with Streptococcus pneumoniae reveals the protective efficacy of carriage in healthy adults. - Wikidata - awgldk - TriplyDB

Controlled human infection and rechallenge with Streptococcus pneumoniae reveals the protective efficacy of carriage in healthy adults.

Controlled human infection and rechallenge with Streptococcus pneumoniae reveals the protective efficacy of carriage in healthy adults.

http://www.wikidata.org/entity/Q36999810

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Correlates of Protection for M Protein-Based Vaccines against Group A Streptococcus The host immune dynamics of pneumococcal colonization: implications for novel vaccine development The Alpha-Tocopherol Form of Vitamin E Boosts Elastase Activity of Human PMNs and Their Ability to Kill Streptococcus pneumoniae.Impact of experimental human pneumococcal carriage on nasopharyngeal bacterial densities in healthy adults.Pathogen evolution and the immunological niche.Serological response to 13-valent pneumococcal conjugate vaccine in children and adolescents with perinatally acquired HIV infection.Density and duration of pneumococcal carriage is maintained by transforming growth factor β1 and T regulatory cells Expression of Streptococcus pneumoniae Virulence-Related Genes in the Nasopharynx of Healthy Children The adult nasopharyngeal microbiome as a determinant of pneumococcal acquisition.Low prevalence of pneumococcal carriage and high serotype and genotype diversity among adults over 60 years of age living in Portugal.Protection against Streptococcus pneumoniae lung infection after nasopharyngeal colonization requires both humoral and cellular immune responses Update in sepsis and pulmonary infections 2013.Unveiling time in dose-response models to infer host susceptibility to pathogens.Delayed reconstitution of B cell immunity to pneumococcus in HIV-infected Malawian children on antiretroviral therapy.Clinical and Microbiological Factors Associated with High Nasopharyngeal Pneumococcal Density in Patients with Pneumococcal Pneumonia.Genetic stability of pneumococcal isolates during 35 days of human experimental carriage Naturally Acquired Human Immunity to Pneumococcus Is Dependent on Antibody to Protein Antigens.Modulation of nasopharyngeal innate defenses by viral coinfection predisposes individuals to experimental pneumococcal carriage Pneumococcal Colonization Rates in Patients Admitted to a United Kingdom Hospital with Lower Respiratory Tract Infection: a Prospective Case-Control Study.Increased IgG but normal IgA anti-pneumococcal protein antibodies in lung of HIV-infected adults CD4 T cell memory and antibody responses directed against the pneumococcal histidine triad proteins PhtD and PhtE following nasopharyngeal colonization and immunization and their role in protection against pneumococcal colonization in mice.Neuraminidase A-Exposed Galactose Promotes Streptococcus pneumoniae Biofilm Formation during Colonization.Rationale and prospects for novel pneumococcal vaccines.Polysaccharide-Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage Agglutination by anti-capsular polysaccharide antibody is associated with protection against experimental human pneumococcal carriage.Staphylococcus aureus Colonization: Modulation of Host Immune Response and Impact on Human Vaccine Design.Age-related immune response to pneumococcal polysaccharide vaccination: lessons for the clinic.Nasopharyngeal colonization with Streptococcus pneumoniae triggers dendritic cell dependent antibody responses against invasive disease in mice.Pneumococcal Capsular Polysaccharide Immunity in the Elderly.First human challenge testing of a pneumococcal vaccine. Double-blind randomized controlled trial.Macrophage migration inhibitory factor promotes clearance of pneumococcal colonization Protection against Streptococcus pneumoniae Invasive Pathogenesis by a Protein-Based Vaccine Is Achieved by Suppression of Nasopharyngeal Bacterial Density during Influenza A Virus Coinfection.Were Antibody Titers the Right Parameter When Immunologically Comparing Pneumococcal Vaccines?Antibody Response is More Likely to Pneumococcal Proteins Than to Polysaccharide After HIV-associated Invasive Pneumococcal Disease.Absence of Streptococcus pneumoniae in pharyngeal swabs of geriatric inpatients.Promises and pitfalls of live attenuated pneumococcal vaccines.A milestone in the investigation of population-wide effects of vaccines.The immunological mechanisms that control pneumococcal carriage.Pneumococcal conjugate vaccine 13 delivered as one primary and one booster dose (1 + 1) compared with two primary doses and a booster (2 + 1) in UK infants: a multicentre, parallel group randomised controlled trial.Streptococcus pneumoniae: transmission, colonization and invasion.

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Controlled human infection and rechallenge with Streptococcus pneumoniae reveals the protective efficacy of carriage in healthy adults.

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RCCM.201212-2277OC

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American Journal of Respiratory and Critical Care Medicine

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Controlled human infection and ...... of carriage in healthy adults.

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Adam K A Wright

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Adriana T Moreno

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Andrea M Collins

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Angela D Wright

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Jenna F Gritzfeld

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Laura Bricio-Moreno

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Nicola Green

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P2860

Are anticapsular antibodies the primary mechanism of protection against invasive pneumococcal disease?

Comparison of a new multiplex binding assay versus the enzyme-linked immunosorbent assay for measurement of serotype-specific pneumococcal capsular polysaccharide IgG

Protective contributions against invasive Streptococcus pneumoniae pneumonia of antibody and Th17-cell responses to nasopharyngeal colonisation

Interleukin-17A mediates acquired immunity to pneumococcal colonization

Immunization of mice with single PspA fragments induces antibodies capable of mediating complement deposition on different pneumococcal strains and cross-protection.

Potential role for mucosally active vaccines against pneumococcal pneumonia

Comparison between nasopharyngeal swab and nasal wash, using culture and PCR, in the detection of potential respiratory pathogens.

CD4+ T cells mediate antibody-independent acquired immunity to pneumococcal colonization.

Characterisation of regulatory T cells in nasal associated lymphoid tissue in children: relationships with pneumococcal colonization.

Human nasal challenge with Streptococcus pneumoniae is immunising in the absence of carriage.

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855-864

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10.1164/RCCM.201212-2277OC

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Daniel R. Neill

Mathieu Bangert

David Goldblatt

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Eliane N Miyaji

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2013-04-01T00:00:00Z

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