Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. - Wikidata - awgldk - TriplyDB

Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma.

Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma.

http://www.wikidata.org/entity/Q37002410

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MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics A small-molecule smoothened agonist prevents glucocorticoid-induced neonatal cerebellar injury Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination Medulloblastoma stem cells: Promising targets in medulloblastoma therapy Emerging functions of the Quaking RNA-binding proteins and link to human diseases Energy metabolism in neurodevelopment and medulloblastoma The role of the ubiquitin proteasome system in cerebellar development and medulloblastoma In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studies An integrative view on sex differences in brain tumors Cytomegalovirus in human brain tumors: Role in pathogenesis and potential treatment options Developmental origins of brain tumors Adaptations of energy metabolism during cerebellar neurogenesis are co-opted in medulloblastoma Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis.Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation.DISP3 promotes proliferation and delays differentiation of neural progenitor cells Control of the Normal and Pathological Development of Neural Stem and Progenitor Cells by the PC3/Tis21/Btg2 and Btg1 Genes Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination Subtypes of medulloblastoma have distinct developmental origins Phosphorylation state of Olig2 regulates proliferation of neural progenitors The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma Oligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brain Cerebellar cortical lamination and foliation require cyclin A2 Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS Persistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity.A distinct Smoothened mutation causes severe cerebellar developmental defects and medulloblastoma in a novel transgenic mouse model In vivo Mn-enhanced MRI for early tumor detection and growth rate analysis in a mouse medulloblastoma model.Ablation of NG2 proteoglycan leads to deficits in brown fat function and to adult onset obesity.Increased epithelial stem cell traits in advanced endometrial endometrioid carcinoma.A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2.Activation of Sonic hedgehog signaling in neural progenitor cells promotes glioma development in the zebrafish optic pathway The prenatal origins of cancer Oligodendrocyte precursors migrate along vasculature in the developing nervous system.Curcumin-induced HDAC inhibition and attenuation of medulloblastoma growth in vitro and in vivo.Pten loss in Olig2 expressing neural progenitor cells and oligodendrocytes leads to interneuron dysplasia and leukodystrophy.β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells.Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells Dexamethasone destabilizes Nmyc to inhibit the growth of hedgehog-associated medulloblastoma Astroglial cells in the external granular layer are precursors of cerebellar granule neurons in neonates Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis.

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Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma.

http://www.wikidata.org/entity/Q37002410

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on August 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Acquisition of granule neuron ...... m Shh-induced medulloblastoma.

@en

Acquisition of granule neuron ...... m Shh-induced medulloblastoma.

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type

label

Acquisition of granule neuron ...... m Shh-induced medulloblastoma.

@en

Acquisition of granule neuron ...... m Shh-induced medulloblastoma.

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prefLabel

Acquisition of granule neuron ...... m Shh-induced medulloblastoma.

@en

Acquisition of granule neuron ...... m Shh-induced medulloblastoma.

@nl

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J.CCR.2008.07.005

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Acquisition of granule neuron ...... m Shh-induced medulloblastoma.

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Allison K Dillon

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Alvin T Kho

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Andrew P McMahon

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Azra H Ligon

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Emmanuelle Huillard

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Junhao Mao

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Qiufu Ma

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Tao Sun

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Ying Qian

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P2860

Development of NG2 neural progenitor cells requires Olig gene function

Cancerous stem cells can arise from pediatric brain tumors

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

Stem cells, cancer, and cancer stem cells

Identification of human brain tumour initiating cells

Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma

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123-134

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10.1016/J.CCR.2008.07.005

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2

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14

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Arturo Álvarez-Buylla

Ulrich Schüller

David H Rowitch

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2008-08-01T00:00:00Z

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23160227

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18691547

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medulloblastoma

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2597270

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