Piperaquine Monotherapy of Drug-Susceptible Plasmodium falciparum Infection Results in Rapid Clearance of Parasitemia but Is Followed by the Appearance of Gametocytemia.
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Plasmodium vivax Controlled Human Malaria Infection - Progress and ProspectsNew developments in anti-malarial target candidate and product profilesInitiation of gametocytogenesis at very low parasite density in Plasmodium falciparum infection.Multiplex, DNase-free one-step reverse transcription PCR for Plasmodium 18S rRNA and spliced gametocyte-specific mRNAs.Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study.Developing transmission-blocking strategies for malaria control.Pharmacokinetic/pharmacodynamic modelling of the antimalarial effect of Actelion-451840 in an induced blood stage malaria study in healthy subjects.A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study.High prevalence of Plasmodium falciparum gametocyte infections in school-age children using molecular detection: patterns and predictors of risk from a cross-sectional study in southern Malawi.Estimation of the In Vivo MIC of Cipargamin in Uncomplicated Plasmodium falciparum Malaria.Concentration of Plasmodium falciparum gametocytes in whole blood samples by magnetic cell sorting enhances parasite infection rates in mosquito feeding assays.Controlled Human Malaria Infection: Applications, Advances and Challenges.Modelling mosquito infection at natural parasite densities identifies drugs targeting EF2, PI4K or ATP4 as key candidates for interrupting malaria transmission.A controlled human malaria infection model enabling evaluation of transmission-blocking interventions.A randomized feasibility trial comparing four antimalarial drug regimens to induce Plasmodium falciparum gametocytemia in the controlled human malaria infection model.Plasmodium Gametocytes in Field Studies: Do We Measure Commitment to Transmission or Detectability?What goes around comes around: modeling malaria transmission from humans back to mosquitos.Assessing Plasmodium falciparum transmission in mosquito-feeding assays using quantitative PCR.Metabolism of Piperaquine to Its Antiplasmodial Metabolites and Their Pharmacokinetic Profiles in Healthy VolunteersDevelopment of medicines for the control and elimination of malaria
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P2860
Piperaquine Monotherapy of Drug-Susceptible Plasmodium falciparum Infection Results in Rapid Clearance of Parasitemia but Is Followed by the Appearance of Gametocytemia.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 07 April 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Piperaquine Monotherapy of Dru ...... e Appearance of Gametocytemia.
@en
Piperaquine Monotherapy of Dru ...... e Appearance of Gametocytemia.
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type
label
Piperaquine Monotherapy of Dru ...... e Appearance of Gametocytemia.
@en
Piperaquine Monotherapy of Dru ...... e Appearance of Gametocytemia.
@nl
prefLabel
Piperaquine Monotherapy of Dru ...... e Appearance of Gametocytemia.
@en
Piperaquine Monotherapy of Dru ...... e Appearance of Gametocytemia.
@nl
P2093
P2860
P356
P1476
Piperaquine Monotherapy of Dru ...... he Appearance of Gametocytemia
@en
P2093
Christopher Peatey
Cielo J Pasay
Claire Y T Wang
Jörg J Möhrle
Louise Marquart
Mark Baker
Peter O'Rourke
Rebecca Rockett
Silvana Sekuloski
Suzanne Elliott
P2860
P304
P356
10.1093/INFDIS/JIW128
P407
P577
2016-04-07T00:00:00Z